Impaired Extinction of Learned Contextual Fear Memory in Early Growth Response 1 Knockout Mice

Inductive expression of early growth response 1 (Egr-1) in neurons is associated with many forms of neuronal activity. However, only a few Egr-1 target genes are known in the brain. The results of this study demonstrate that Egr-1 knockout (KO) mice display impaired contextual extinction learning an...

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Veröffentlicht in:Molecules and cells 2014, Vol.37 (1), p.24-30
Hauptverfasser: Han, Seungrie, Hong, Soontaek, Mo, Jiwon, Lee, Dongmin, Choi, Eunju, Choi, June-Seek, Sun, Woong, Lee, Hyun Woo, Kim, Hyun
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Sprache:kor
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