Adenovirus Expressing Human Interferon Inhibits Replication of Foot and Mouth Disease Virus and Reduces Fatal Rate in Mice
Interferon is an important cytokine that plays a critical role in the initial host defense against viral infection. Recombinant human adenoviruses expressing human interferon-A (Ad-HIFNA) or pig interferon-B fused with interleukin-18 (Ad-PIFNB-IL18) were constructed and used to induce an early prote...
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Veröffentlicht in: | Journal of bacteriology and virology 2012-09, Vol.42 (3), p.224-231 |
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