Mechanism Studies of Substituted Triazol-1-yl-pyrimidine Derivatives Inhibition on Mycobacterium tuberculosis Acetohydroxyacid Synthase

The first step in the common pathway for the biosynthesis of branched chain amino acids is catalyzed by acetohydroxyacid synthase (AHAS). The AHAS is found in plants, fungi and bacteria. With an aim to identify new anti-tuberculosis drugs that inhibit branched chain amino acid biosynthesis, we scree...

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Veröffentlicht in:	Bulletin of the Korean Chemical Society 2012, Vol.33 (12), p.4074-4078
Hauptverfasser:	Chien, Pham Ngoc, Jung, In-Pil, Reddy, Katta Venugopal, Yoon, Moon-Young
Format:	Artikel
Sprache:	kor
Online-Zugang:	Volltext
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