The effect of surface charge balance on thermodynamic stability and kinetics of refolding of firefly Luciferase

Thermodynamic stability and refolding kinetics of firefly luciferase and three representative mutants with depletion of negative charge on a flexible loop via substitution of Glu by Arg(ER mutant) or Lys (EK mutant) as well as insertion of another Arg in ER mutants (ERR mutant) was investigated. Acc...

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Veröffentlicht in:	BMB reports 2011-02, Vol.44 (2), p.102-106
Hauptverfasser:	Khalifeh, Khosrow, Ranjbar, Bijan, Alipour, Bagher Said, Hosseinkhani, Saman
Format:	Artikel
Sprache:	kor
Schlagworte:	Aggregation Kinetics Luciferase Refolding Thermodynamic stability
Online-Zugang:	Volltext
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