Mesenchymal Stem Cells Modified with Stromal Cell-Derived Factor 1${\alpha}$ Improve Cardiac Remodeling via Paracrine Activation of Hepatocyte Growth Factor in a Rat Model of Myocardial Infarction
Mesenchymal stem cells (MSCs) are a promising source for cell-based treatment of myocardial infarction (MI), but existing strategies are restricted by low cell survival and engraftment. We examined whether SDF-1 transfection improve MSC viability and paracrine action in infarcted hearts. We found SD...
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Veröffentlicht in: | Molecules and cells 2010, Vol.29 (1), p.9-19 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | kor |
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