Mesenchymal Stem Cells Modified with Stromal Cell-Derived Factor 1${\alpha}$ Improve Cardiac Remodeling via Paracrine Activation of Hepatocyte Growth Factor in a Rat Model of Myocardial Infarction

Mesenchymal stem cells (MSCs) are a promising source for cell-based treatment of myocardial infarction (MI), but existing strategies are restricted by low cell survival and engraftment. We examined whether SDF-1 transfection improve MSC viability and paracrine action in infarcted hearts. We found SD...

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Veröffentlicht in:Molecules and cells 2010, Vol.29 (1), p.9-19
Hauptverfasser: Tang, Junming, Wang, Jianing, Guo, Linyun, Kong, Xia, Yang, Jianye, Zheng, Fei, Zhang, Lei, Huang, Yongzhang
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Sprache:kor
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