Possible roles of amyloid intracellular domain of amyloid precursor protein

Amyloid precursor protein (APP), which is critically involved in the pathogenesis of Alzheimer's disease (AD), is cleaved by gamma/epsilon-secretase activity and results in the generation of different lengths of the APP Intracellular C-terminal Domain (AICD). In spite of its small size and shor...

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Veröffentlicht in:	BMB reports 2010, Vol.43 (10), p.656-663
Hauptverfasser:	Chang, Keun-A, Suh, Yoo-Hun
Format:	Artikel
Sprache:	kor
Online-Zugang:	Volltext
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