3D Quantitative and Qualitative Structure-Activity Relationships of the δ -Opioid Receptor Antagonists

Antagonists of the d -opioid receptor are effective in overcoming resistance against analgesic drugs such as morphine. To identify novel antagonists of the d -opioid receptor that display high potency and low resistance, we performed 3D-QSAR analysis using chemical feature-based pharmacophore models...

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Veröffentlicht in:Bulletin of the Korean Chemical Society 2008, Vol.29 (3), p.656-662
Hauptverfasser: Chun, Sun, Lee, Jee-Young, Ro, Seong-Gu, Jeong, Ki-Woong, Kim, Yang-Mee, Yoon, Chang-Ju
Format: Artikel
Sprache:kor
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