녹차 결명자 추출물의 교정용 브라켓과 치면 사이의 경계부에서 분리된 mutans streptococci에 대한 항균작용
Mutans streptococci is the major causative factor in dental caries. Especially, orthodontic patients with fixed appliance are a risk group for dental caries. Because fixed appliances attached on teeth may change the environment of dental plaque, the enamel decalcification or dental caries around the...
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| Veröffentlicht in: | Korean journal of orthodontics 2003, Vol.33 (5), p.381-389 |
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| creator | 임성훈 서정순 윤영주 김광원 유소영 김화숙 국중기 이병래 차종희 박재윤 Lim, Sung-Hoon Seo, Jeong-Soon Yoon, Young-Jooh Kim, Kwang-Won Yoon, So Young Kim, Hwa-Sook Kook, Joong-Ki Lee, Byoung-Rai Cha, Jong-Hee Park, Jae-Yoon |
| description | Mutans streptococci is the major causative factor in dental caries. Especially, orthodontic patients with fixed appliance are a risk group for dental caries. Because fixed appliances attached on teeth may change the environment of dental plaque, the enamel decalcification or dental caries around the bracket and band is a major side effect of orthodontic treatmet. The aim of this study was to search plant extracts that have antimicrobial effect on mutans streptococci. Seed-extract of Casia torn were prepared with ethanol and CHMC-2032, the leaf-extracts from Camellia sinensis extract, was obtained extract, 2 type strains and 20 clinical isolates of mutans streptococci isolated from the interface between orthodontic brackets and tooth surfaces in the orthodontic patients were used in this study. The minimal inhibitory concentration of CHMC-2032 was 5mg/ml on the S. mutans KCTC 3065, S. sobrinus KCTC 3088, and 8 clinical isolates of S. sobrinus. However, there was no antibacterial effect of seed-extract of C. tora on mutans streptococci. These data suggest that green tea nay be more effective than the tea Prepared from C tora In the prevention of enamel decalcification or dental caries around brackets. 본 연구는 치아우식증에 관련된 Hutans streptococci 표준균주 및 임상분리 균주의 성장억제를 유도할 수 있는 천연생약추출물을 검색하기 위하여 실시되었다. 녹차추출물은 CHMC-2032를 사용하였으며, 결명자 추출물은 $50\%$ 에탄올을 이용하여얻었다. 이들 추출물의 Mutans streptococci표준균주 및 교정환자들에서 브라켓과 치면 사이의 경계부에서 분리된 각각 10 균주씩의 S. mutans 및 S. sobrinus에 대한 최소성장억제농도를 액체배지 희석법으로 구하였다. 그 결과 CHMC-2032의 S. mutans 및 S. sobrinus의 표준 균주, S. sobrinus의 대부분 임상분리 균주에 대한 최소성장 억제농도는 5mg/ml이었다 그러나 결명자 추출물에 의한 S. mutans 및 S. sobrinus에 대한 세균 성장억제 효과는 미미하였다. 본 연구 결과 치아우식증의 예방적 측면에서 결명자차보다는 녹차를 마시는 것이 유리하며, CHMC-2032를 이용하여 구강양치용액을 제조하여 사용할 경우 교정환자를 포함하여 대부분의 사람에게서 치아우식증 예방 효과가 있으리고 추정된다. |
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Especially, orthodontic patients with fixed appliance are a risk group for dental caries. Because fixed appliances attached on teeth may change the environment of dental plaque, the enamel decalcification or dental caries around the bracket and band is a major side effect of orthodontic treatmet. The aim of this study was to search plant extracts that have antimicrobial effect on mutans streptococci. Seed-extract of Casia torn were prepared with ethanol and CHMC-2032, the leaf-extracts from Camellia sinensis extract, was obtained extract, 2 type strains and 20 clinical isolates of mutans streptococci isolated from the interface between orthodontic brackets and tooth surfaces in the orthodontic patients were used in this study. The minimal inhibitory concentration of CHMC-2032 was 5mg/ml on the S. mutans KCTC 3065, S. sobrinus KCTC 3088, and 8 clinical isolates of S. sobrinus. However, there was no antibacterial effect of seed-extract of C. tora on mutans streptococci. These data suggest that green tea nay be more effective than the tea Prepared from C tora In the prevention of enamel decalcification or dental caries around brackets. 본 연구는 치아우식증에 관련된 Hutans streptococci 표준균주 및 임상분리 균주의 성장억제를 유도할 수 있는 천연생약추출물을 검색하기 위하여 실시되었다. 녹차추출물은 CHMC-2032를 사용하였으며, 결명자 추출물은 $50\%$ 에탄올을 이용하여얻었다. 이들 추출물의 Mutans streptococci표준균주 및 교정환자들에서 브라켓과 치면 사이의 경계부에서 분리된 각각 10 균주씩의 S. mutans 및 S. sobrinus에 대한 최소성장억제농도를 액체배지 희석법으로 구하였다. 그 결과 CHMC-2032의 S. mutans 및 S. sobrinus의 표준 균주, S. sobrinus의 대부분 임상분리 균주에 대한 최소성장 억제농도는 5mg/ml이었다 그러나 결명자 추출물에 의한 S. mutans 및 S. sobrinus에 대한 세균 성장억제 효과는 미미하였다. 본 연구 결과 치아우식증의 예방적 측면에서 결명자차보다는 녹차를 마시는 것이 유리하며, CHMC-2032를 이용하여 구강양치용액을 제조하여 사용할 경우 교정환자를 포함하여 대부분의 사람에게서 치아우식증 예방 효과가 있으리고 추정된다.</description><identifier>ISSN: 1225-5610</identifier><identifier>EISSN: 2005-372X</identifier><language>kor</language><ispartof>Korean journal of orthodontics, 2003, Vol.33 (5), p.381-389</ispartof><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,781,785,886,4025</link.rule.ids></links><search><creatorcontrib>임성훈</creatorcontrib><creatorcontrib>서정순</creatorcontrib><creatorcontrib>윤영주</creatorcontrib><creatorcontrib>김광원</creatorcontrib><creatorcontrib>유소영</creatorcontrib><creatorcontrib>김화숙</creatorcontrib><creatorcontrib>국중기</creatorcontrib><creatorcontrib>이병래</creatorcontrib><creatorcontrib>차종희</creatorcontrib><creatorcontrib>박재윤</creatorcontrib><creatorcontrib>Lim, Sung-Hoon</creatorcontrib><creatorcontrib>Seo, Jeong-Soon</creatorcontrib><creatorcontrib>Yoon, Young-Jooh</creatorcontrib><creatorcontrib>Kim, Kwang-Won</creatorcontrib><creatorcontrib>Yoon, So Young</creatorcontrib><creatorcontrib>Kim, Hwa-Sook</creatorcontrib><creatorcontrib>Kook, Joong-Ki</creatorcontrib><creatorcontrib>Lee, Byoung-Rai</creatorcontrib><creatorcontrib>Cha, Jong-Hee</creatorcontrib><creatorcontrib>Park, Jae-Yoon</creatorcontrib><title>녹차 결명자 추출물의 교정용 브라켓과 치면 사이의 경계부에서 분리된 mutans streptococci에 대한 항균작용</title><title>Korean journal of orthodontics</title><addtitle>Korean journal of orthodontics</addtitle><description>Mutans streptococci is the major causative factor in dental caries. Especially, orthodontic patients with fixed appliance are a risk group for dental caries. Because fixed appliances attached on teeth may change the environment of dental plaque, the enamel decalcification or dental caries around the bracket and band is a major side effect of orthodontic treatmet. The aim of this study was to search plant extracts that have antimicrobial effect on mutans streptococci. Seed-extract of Casia torn were prepared with ethanol and CHMC-2032, the leaf-extracts from Camellia sinensis extract, was obtained extract, 2 type strains and 20 clinical isolates of mutans streptococci isolated from the interface between orthodontic brackets and tooth surfaces in the orthodontic patients were used in this study. The minimal inhibitory concentration of CHMC-2032 was 5mg/ml on the S. mutans KCTC 3065, S. sobrinus KCTC 3088, and 8 clinical isolates of S. sobrinus. However, there was no antibacterial effect of seed-extract of C. tora on mutans streptococci. These data suggest that green tea nay be more effective than the tea Prepared from C tora In the prevention of enamel decalcification or dental caries around brackets. 본 연구는 치아우식증에 관련된 Hutans streptococci 표준균주 및 임상분리 균주의 성장억제를 유도할 수 있는 천연생약추출물을 검색하기 위하여 실시되었다. 녹차추출물은 CHMC-2032를 사용하였으며, 결명자 추출물은 $50\%$ 에탄올을 이용하여얻었다. 이들 추출물의 Mutans streptococci표준균주 및 교정환자들에서 브라켓과 치면 사이의 경계부에서 분리된 각각 10 균주씩의 S. mutans 및 S. sobrinus에 대한 최소성장억제농도를 액체배지 희석법으로 구하였다. 그 결과 CHMC-2032의 S. mutans 및 S. sobrinus의 표준 균주, S. sobrinus의 대부분 임상분리 균주에 대한 최소성장 억제농도는 5mg/ml이었다 그러나 결명자 추출물에 의한 S. mutans 및 S. sobrinus에 대한 세균 성장억제 효과는 미미하였다. 본 연구 결과 치아우식증의 예방적 측면에서 결명자차보다는 녹차를 마시는 것이 유리하며, CHMC-2032를 이용하여 구강양치용액을 제조하여 사용할 경우 교정환자를 포함하여 대부분의 사람에게서 치아우식증 예방 효과가 있으리고 추정된다.</description><issn>1225-5610</issn><issn>2005-372X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>JDI</sourceid><recordid>eNpjYuA0MjAw1TU2N4pgYeA0NDIy1TU1MzTgYOAtLs5MMjC2MDA3M7Qw4WToet26882GFQqvNm14var1zbwJCm-2TXmzbc7rNXvezJ2h8GrrhDcLpr6ZtVLh9Y6e13P3vNkz-dXmPQpvds54vXKLwpumNW_mbgGr27T31eaW19sa3kyf8KZljsLrbS2vl615PWGOQm5pSWJesUJxSVFqQUl-cn5yciZQjcLrnoa3U-covJ269tX2BW_mTQRawcPAmpaYU5zKC6W5GVTdXEOcPXSzM4tLMuPzUopz4r0cvf2BPjM2sLAwMjY3MzewNDQmVh0AV4J5Ng</recordid><startdate>2003</startdate><enddate>2003</enddate><creator>임성훈</creator><creator>서정순</creator><creator>윤영주</creator><creator>김광원</creator><creator>유소영</creator><creator>김화숙</creator><creator>국중기</creator><creator>이병래</creator><creator>차종희</creator><creator>박재윤</creator><creator>Lim, Sung-Hoon</creator><creator>Seo, Jeong-Soon</creator><creator>Yoon, Young-Jooh</creator><creator>Kim, Kwang-Won</creator><creator>Yoon, So Young</creator><creator>Kim, Hwa-Sook</creator><creator>Kook, Joong-Ki</creator><creator>Lee, Byoung-Rai</creator><creator>Cha, Jong-Hee</creator><creator>Park, Jae-Yoon</creator><scope>JDI</scope></search><sort><creationdate>2003</creationdate><title>녹차 결명자 추출물의 교정용 브라켓과 치면 사이의 경계부에서 분리된 mutans streptococci에 대한 항균작용</title><author>임성훈 ; 서정순 ; 윤영주 ; 김광원 ; 유소영 ; 김화숙 ; 국중기 ; 이병래 ; 차종희 ; 박재윤 ; Lim, Sung-Hoon ; Seo, Jeong-Soon ; Yoon, Young-Jooh ; Kim, Kwang-Won ; Yoon, So Young ; Kim, Hwa-Sook ; Kook, Joong-Ki ; Lee, Byoung-Rai ; Cha, Jong-Hee ; Park, Jae-Yoon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-kisti_ndsl_JAKO2003088237670913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>2003</creationdate><toplevel>online_resources</toplevel><creatorcontrib>임성훈</creatorcontrib><creatorcontrib>서정순</creatorcontrib><creatorcontrib>윤영주</creatorcontrib><creatorcontrib>김광원</creatorcontrib><creatorcontrib>유소영</creatorcontrib><creatorcontrib>김화숙</creatorcontrib><creatorcontrib>국중기</creatorcontrib><creatorcontrib>이병래</creatorcontrib><creatorcontrib>차종희</creatorcontrib><creatorcontrib>박재윤</creatorcontrib><creatorcontrib>Lim, Sung-Hoon</creatorcontrib><creatorcontrib>Seo, Jeong-Soon</creatorcontrib><creatorcontrib>Yoon, Young-Jooh</creatorcontrib><creatorcontrib>Kim, Kwang-Won</creatorcontrib><creatorcontrib>Yoon, So Young</creatorcontrib><creatorcontrib>Kim, Hwa-Sook</creatorcontrib><creatorcontrib>Kook, Joong-Ki</creatorcontrib><creatorcontrib>Lee, Byoung-Rai</creatorcontrib><creatorcontrib>Cha, Jong-Hee</creatorcontrib><creatorcontrib>Park, Jae-Yoon</creatorcontrib><collection>KoreaScience</collection><jtitle>Korean journal of orthodontics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>임성훈</au><au>서정순</au><au>윤영주</au><au>김광원</au><au>유소영</au><au>김화숙</au><au>국중기</au><au>이병래</au><au>차종희</au><au>박재윤</au><au>Lim, Sung-Hoon</au><au>Seo, Jeong-Soon</au><au>Yoon, Young-Jooh</au><au>Kim, Kwang-Won</au><au>Yoon, So Young</au><au>Kim, Hwa-Sook</au><au>Kook, Joong-Ki</au><au>Lee, Byoung-Rai</au><au>Cha, Jong-Hee</au><au>Park, Jae-Yoon</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>녹차 결명자 추출물의 교정용 브라켓과 치면 사이의 경계부에서 분리된 mutans streptococci에 대한 항균작용</atitle><jtitle>Korean journal of orthodontics</jtitle><addtitle>Korean journal of orthodontics</addtitle><date>2003</date><risdate>2003</risdate><volume>33</volume><issue>5</issue><spage>381</spage><epage>389</epage><pages>381-389</pages><issn>1225-5610</issn><eissn>2005-372X</eissn><abstract>Mutans streptococci is the major causative factor in dental caries. Especially, orthodontic patients with fixed appliance are a risk group for dental caries. Because fixed appliances attached on teeth may change the environment of dental plaque, the enamel decalcification or dental caries around the bracket and band is a major side effect of orthodontic treatmet. The aim of this study was to search plant extracts that have antimicrobial effect on mutans streptococci. Seed-extract of Casia torn were prepared with ethanol and CHMC-2032, the leaf-extracts from Camellia sinensis extract, was obtained extract, 2 type strains and 20 clinical isolates of mutans streptococci isolated from the interface between orthodontic brackets and tooth surfaces in the orthodontic patients were used in this study. The minimal inhibitory concentration of CHMC-2032 was 5mg/ml on the S. mutans KCTC 3065, S. sobrinus KCTC 3088, and 8 clinical isolates of S. sobrinus. However, there was no antibacterial effect of seed-extract of C. tora on mutans streptococci. These data suggest that green tea nay be more effective than the tea Prepared from C tora In the prevention of enamel decalcification or dental caries around brackets. 본 연구는 치아우식증에 관련된 Hutans streptococci 표준균주 및 임상분리 균주의 성장억제를 유도할 수 있는 천연생약추출물을 검색하기 위하여 실시되었다. 녹차추출물은 CHMC-2032를 사용하였으며, 결명자 추출물은 $50\%$ 에탄올을 이용하여얻었다. 이들 추출물의 Mutans streptococci표준균주 및 교정환자들에서 브라켓과 치면 사이의 경계부에서 분리된 각각 10 균주씩의 S. mutans 및 S. sobrinus에 대한 최소성장억제농도를 액체배지 희석법으로 구하였다. 그 결과 CHMC-2032의 S. mutans 및 S. sobrinus의 표준 균주, S. sobrinus의 대부분 임상분리 균주에 대한 최소성장 억제농도는 5mg/ml이었다 그러나 결명자 추출물에 의한 S. mutans 및 S. sobrinus에 대한 세균 성장억제 효과는 미미하였다. 본 연구 결과 치아우식증의 예방적 측면에서 결명자차보다는 녹차를 마시는 것이 유리하며, CHMC-2032를 이용하여 구강양치용액을 제조하여 사용할 경우 교정환자를 포함하여 대부분의 사람에게서 치아우식증 예방 효과가 있으리고 추정된다.</abstract><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1225-5610 |
| ispartof | Korean journal of orthodontics, 2003, Vol.33 (5), p.381-389 |
| issn | 1225-5610 2005-372X |
| language | kor |
| recordid | cdi_kisti_ndsl_JAKO200308823767091 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; KoreaMed Open Access; Alma/SFX Local Collection |
| title | 녹차 결명자 추출물의 교정용 브라켓과 치면 사이의 경계부에서 분리된 mutans streptococci에 대한 항균작용 |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T17%3A10%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-kisti&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=%EB%85%B9%EC%B0%A8%20%EA%B2%B0%EB%AA%85%EC%9E%90%20%EC%B6%94%EC%B6%9C%EB%AC%BC%EC%9D%98%20%EA%B5%90%EC%A0%95%EC%9A%A9%20%EB%B8%8C%EB%9D%BC%EC%BC%93%EA%B3%BC%20%EC%B9%98%EB%A9%B4%20%EC%82%AC%EC%9D%B4%EC%9D%98%20%EA%B2%BD%EA%B3%84%EB%B6%80%EC%97%90%EC%84%9C%20%EB%B6%84%EB%A6%AC%EB%90%9C%20mutans%20streptococci%EC%97%90%20%EB%8C%80%ED%95%9C%20%ED%95%AD%EA%B7%A0%EC%9E%91%EC%9A%A9&rft.jtitle=Korean%20journal%20of%20orthodontics&rft.au=%EC%9E%84%EC%84%B1%ED%9B%88&rft.date=2003&rft.volume=33&rft.issue=5&rft.spage=381&rft.epage=389&rft.pages=381-389&rft.issn=1225-5610&rft.eissn=2005-372X&rft_id=info:doi/&rft_dat=%3Ckisti%3EJAKO200308823767091%3C/kisti%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |