한국인 기호 차류의 방사선 장해 경감효과 평가
We performed this study to determine the effect of Korean favorite teas (green tea, ginseng tea, coffee and barley tea) on jejunal crypt survival, endogenous spleen colony formation and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of ${\gamma}$-radiation. Jejunal crypts...
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| Veröffentlicht in: | Taehan Suŭi Hakhoe chi 2002, Vol.42 (4), p.475-483 |
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| creator | 김세라 이해준 오헌 이진희 김휴경 김태환 조성기 김성호 Kim, Se-Ra Lee, Hae-June Oh, Heon Lee, Jin-Hee Kim, Hu-Kyung Kim, Tae-Hwan Jo, Sung-Kee Kim, Sung-Ho |
| description | We performed this study to determine the effect of Korean favorite teas (green tea, ginseng tea, coffee and barley tea) on jejunal crypt survival, endogenous spleen colony formation and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of ${\gamma}$-radiation. Jejunal crypts were protected by pretreatment of green tea (P.O.: 1.25% water extract, for 7 days before irradiation., I.P.: 50 mg/kg of body weight, at 12 and 36 hours before irradiation, p |
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Jejunal crypts were protected by pretreatment of green tea (P.O.: 1.25% water extract, for 7 days before irradiation., I.P.: 50 mg/kg of body weight, at 12 and 36 hours before irradiation, p<0.01) or ginseng (I.P.: 50 mg/kg of body weight, at 12 and 36 hours before irradiation, p<0.05). Green tea (p<0.05) or ginseng (p<0.05) administration before irradiation (I.P. at 12 and 36 hours before irradiation) resulted in an increase of t formation of endogenous spleen colony. The frequency of radiation-induced apoptosis was also reduced by pretreatment of green tea (P.O.: p<0.005, I.P.: p<0.05), pretreatment of ginseng (P.O.: p<0.005, I.P.: p<0.005) or posttreatment of ginseng (I.P.: 50 mg/kg of body weight, at 30 minutes after irradiation, p<0.05). Treatment with coffee or barley tea showed no significant modifying effects on the radiation-induced damages. These results indicated that green tea and ginseng might be a useful radioprotector, especially since it is a relatively nontoxic natural product. Further studies are needed to characterize better the promotion nature of green tea, ginseng and its components.]]></description><identifier>ISSN: 1225-0198</identifier><identifier>EISSN: 2234-134X</identifier><language>kor</language><ispartof>Taehan Suŭi Hakhoe chi, 2002, Vol.42 (4), p.475-483</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,4010</link.rule.ids></links><search><creatorcontrib>김세라</creatorcontrib><creatorcontrib>이해준</creatorcontrib><creatorcontrib>오헌</creatorcontrib><creatorcontrib>이진희</creatorcontrib><creatorcontrib>김휴경</creatorcontrib><creatorcontrib>김태환</creatorcontrib><creatorcontrib>조성기</creatorcontrib><creatorcontrib>김성호</creatorcontrib><creatorcontrib>Kim, Se-Ra</creatorcontrib><creatorcontrib>Lee, Hae-June</creatorcontrib><creatorcontrib>Oh, Heon</creatorcontrib><creatorcontrib>Lee, Jin-Hee</creatorcontrib><creatorcontrib>Kim, Hu-Kyung</creatorcontrib><creatorcontrib>Kim, Tae-Hwan</creatorcontrib><creatorcontrib>Jo, Sung-Kee</creatorcontrib><creatorcontrib>Kim, Sung-Ho</creatorcontrib><title>한국인 기호 차류의 방사선 장해 경감효과 평가</title><title>Taehan Suŭi Hakhoe chi</title><addtitle>Korean journal of veterinary research</addtitle><description><![CDATA[We performed this study to determine the effect of Korean favorite teas (green tea, ginseng tea, coffee and barley tea) on jejunal crypt survival, endogenous spleen colony formation and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of ${\gamma}$-radiation. Jejunal crypts were protected by pretreatment of green tea (P.O.: 1.25% water extract, for 7 days before irradiation., I.P.: 50 mg/kg of body weight, at 12 and 36 hours before irradiation, p<0.01) or ginseng (I.P.: 50 mg/kg of body weight, at 12 and 36 hours before irradiation, p<0.05). Green tea (p<0.05) or ginseng (p<0.05) administration before irradiation (I.P. at 12 and 36 hours before irradiation) resulted in an increase of t formation of endogenous spleen colony. The frequency of radiation-induced apoptosis was also reduced by pretreatment of green tea (P.O.: p<0.005, I.P.: p<0.05), pretreatment of ginseng (P.O.: p<0.005, I.P.: p<0.005) or posttreatment of ginseng (I.P.: 50 mg/kg of body weight, at 30 minutes after irradiation, p<0.05). Treatment with coffee or barley tea showed no significant modifying effects on the radiation-induced damages. These results indicated that green tea and ginseng might be a useful radioprotector, especially since it is a relatively nontoxic natural product. Further studies are needed to characterize better the promotion nature of green tea, ginseng and its components.]]></description><issn>1225-0198</issn><issn>2234-134X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>JDI</sourceid><recordid>eNotzL1KAzEAwPEgCh5t3yGL40G-LzdJKX4XunRwK8nlAkeLy_kAIi5OuhQOseJSqKAQtMIN-kJp8g4KOv1_038LJIRQlmLKzrdBggnhKcK53AW9uq40QhgzKSVOwH6cP_rPt7BooW9dbFoY3GqzbMKigRv3Eq5fw80zDE_LOF9D__7t3X18WPmPLxjvbr276oIdq2Z12ftvB4wPD8aD43Q4OjoZ9IfplBOZWoplqUtprC5txjWnSKjcIMqs5owyJpSQpkBZYfJcZjZjOSlNUVCVaWU1ox2w97edVvVlNbkw9Wxy2j8bEYQIkUgIjsQv6Q_C7Vkf</recordid><startdate>2002</startdate><enddate>2002</enddate><creator>김세라</creator><creator>이해준</creator><creator>오헌</creator><creator>이진희</creator><creator>김휴경</creator><creator>김태환</creator><creator>조성기</creator><creator>김성호</creator><creator>Kim, Se-Ra</creator><creator>Lee, Hae-June</creator><creator>Oh, Heon</creator><creator>Lee, Jin-Hee</creator><creator>Kim, Hu-Kyung</creator><creator>Kim, Tae-Hwan</creator><creator>Jo, Sung-Kee</creator><creator>Kim, Sung-Ho</creator><scope>JDI</scope></search><sort><creationdate>2002</creationdate><title>한국인 기호 차류의 방사선 장해 경감효과 평가</title><author>김세라 ; 이해준 ; 오헌 ; 이진희 ; 김휴경 ; 김태환 ; 조성기 ; 김성호 ; Kim, Se-Ra ; Lee, Hae-June ; Oh, Heon ; Lee, Jin-Hee ; Kim, Hu-Kyung ; Kim, Tae-Hwan ; Jo, Sung-Kee ; Kim, Sung-Ho</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-k528-f318ebe8dfbef75b5306a9d034fb543446a68dc07cd9987f7492edcc3a7bafb43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>2002</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>김세라</creatorcontrib><creatorcontrib>이해준</creatorcontrib><creatorcontrib>오헌</creatorcontrib><creatorcontrib>이진희</creatorcontrib><creatorcontrib>김휴경</creatorcontrib><creatorcontrib>김태환</creatorcontrib><creatorcontrib>조성기</creatorcontrib><creatorcontrib>김성호</creatorcontrib><creatorcontrib>Kim, Se-Ra</creatorcontrib><creatorcontrib>Lee, Hae-June</creatorcontrib><creatorcontrib>Oh, Heon</creatorcontrib><creatorcontrib>Lee, Jin-Hee</creatorcontrib><creatorcontrib>Kim, Hu-Kyung</creatorcontrib><creatorcontrib>Kim, Tae-Hwan</creatorcontrib><creatorcontrib>Jo, Sung-Kee</creatorcontrib><creatorcontrib>Kim, Sung-Ho</creatorcontrib><collection>KoreaScience (Open Access)</collection><jtitle>Taehan Suŭi Hakhoe chi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>김세라</au><au>이해준</au><au>오헌</au><au>이진희</au><au>김휴경</au><au>김태환</au><au>조성기</au><au>김성호</au><au>Kim, Se-Ra</au><au>Lee, Hae-June</au><au>Oh, Heon</au><au>Lee, Jin-Hee</au><au>Kim, Hu-Kyung</au><au>Kim, Tae-Hwan</au><au>Jo, Sung-Kee</au><au>Kim, Sung-Ho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>한국인 기호 차류의 방사선 장해 경감효과 평가</atitle><jtitle>Taehan Suŭi Hakhoe chi</jtitle><addtitle>Korean journal of veterinary research</addtitle><date>2002</date><risdate>2002</risdate><volume>42</volume><issue>4</issue><spage>475</spage><epage>483</epage><pages>475-483</pages><issn>1225-0198</issn><eissn>2234-134X</eissn><abstract><![CDATA[We performed this study to determine the effect of Korean favorite teas (green tea, ginseng tea, coffee and barley tea) on jejunal crypt survival, endogenous spleen colony formation and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of ${\gamma}$-radiation. Jejunal crypts were protected by pretreatment of green tea (P.O.: 1.25% water extract, for 7 days before irradiation., I.P.: 50 mg/kg of body weight, at 12 and 36 hours before irradiation, p<0.01) or ginseng (I.P.: 50 mg/kg of body weight, at 12 and 36 hours before irradiation, p<0.05). Green tea (p<0.05) or ginseng (p<0.05) administration before irradiation (I.P. at 12 and 36 hours before irradiation) resulted in an increase of t formation of endogenous spleen colony. The frequency of radiation-induced apoptosis was also reduced by pretreatment of green tea (P.O.: p<0.005, I.P.: p<0.05), pretreatment of ginseng (P.O.: p<0.005, I.P.: p<0.005) or posttreatment of ginseng (I.P.: 50 mg/kg of body weight, at 30 minutes after irradiation, p<0.05). Treatment with coffee or barley tea showed no significant modifying effects on the radiation-induced damages. These results indicated that green tea and ginseng might be a useful radioprotector, especially since it is a relatively nontoxic natural product. Further studies are needed to characterize better the promotion nature of green tea, ginseng and its components.]]></abstract><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| title | 한국인 기호 차류의 방사선 장해 경감효과 평가 |
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