산오리나무의 세포독성 성분연구
To find out antitumor active principles from natural resources, we have evaluated various extracts from the leaves of Alnus hirsuta (Betulaceae). The ethylacetate extract of this plant was found to show a significant cytotoxicity against several kinds of cultured human solid tumor cell lines (AGS, A...
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| Veröffentlicht in: | Yaghag-hoi-ji 1997-10, Vol.41 (5), p.559-564 |
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| creator | 배춘일(Choon Il Bae) 공재명(Jae Myung Gong) 오정완(Jung Wan Oh) 김현종(Hyun Jong Kim) 오갑진(Gab Jin Oh) 박시경(Si Kyung Park) 정순간(Sun Gan Chung) 조의환(Eui Hwan Cho) |
| description | To find out antitumor active principles from natural resources, we have evaluated various extracts from the leaves of Alnus hirsuta (Betulaceae). The ethylacetate extract of this plant was found to show a significant cytotoxicity against several kinds of cultured human solid tumor cell lines (AGS, A5 49, HCT15, SKOV3, HEP3B) in vitro. Using cytotoxicity-guided chromatographic purification of the ethylacetate extract, cytotoxic constituent:1,7-bis-(4-hydroxyphenyl)-5-(${\beta}$-D-glucopyranosyloxy)-3-heptanone, was isolated and structurally identified by physico-chemical properties and spectroscopic evidences. |
| format | Article |
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Using cytotoxicity-guided chromatographic purification of the ethylacetate extract, cytotoxic constituent:1,7-bis-(4-hydroxyphenyl)-5-(${\beta}$-D-glucopyranosyloxy)-3-heptanone, was isolated and structurally identified by physico-chemical properties and spectroscopic evidences.</description><identifier>ISSN: 0377-9556</identifier><identifier>EISSN: 2383-9457</identifier><language>kor</language><publisher>The Pharmaceutical Society Of Korea</publisher><ispartof>Yaghag-hoi-ji, 1997-10, Vol.41 (5), p.559-564</ispartof><rights>COPYRIGHT(C) KYOBO BOOK CENTRE ALL RIGHTS RESERVED</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885</link.rule.ids></links><search><creatorcontrib>배춘일(Choon Il Bae)</creatorcontrib><creatorcontrib>공재명(Jae Myung Gong)</creatorcontrib><creatorcontrib>오정완(Jung Wan Oh)</creatorcontrib><creatorcontrib>김현종(Hyun Jong Kim)</creatorcontrib><creatorcontrib>오갑진(Gab Jin Oh)</creatorcontrib><creatorcontrib>박시경(Si Kyung Park)</creatorcontrib><creatorcontrib>정순간(Sun Gan Chung)</creatorcontrib><creatorcontrib>조의환(Eui Hwan Cho)</creatorcontrib><title>산오리나무의 세포독성 성분연구</title><title>Yaghag-hoi-ji</title><addtitle>Yakhak hoeji</addtitle><description>To find out antitumor active principles from natural resources, we have evaluated various extracts from the leaves of Alnus hirsuta (Betulaceae). 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Using cytotoxicity-guided chromatographic purification of the ethylacetate extract, cytotoxic constituent:1,7-bis-(4-hydroxyphenyl)-5-(${\beta}$-D-glucopyranosyloxy)-3-heptanone, was isolated and structurally identified by physico-chemical properties and spectroscopic evidences.</description><issn>0377-9556</issn><issn>2383-9457</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>JDI</sourceid><recordid>eNpNjj1Lw0Acxg9RMNR-Bxc3A_-7f-5tLMX3Qpfu4S69g5DSgOniWuLc0Sxu4pShhSp-JnN-hwZ0cHp44Mfze45IxFBhrBMuj0kEKGWsORenZFhVuQUUTCqJPCKXYb0NzVv33nbrpmv34bU5D_XXz6btNs-h3vVl133W4WX7_dGekRNvFpUb_uWAzK6vZuPbeDK9uRuPJnEhAOO5cUZZxZ1nimpBe5uS3vhEZl4CAiScKWUYUieZNSAsdYZCBtojNV7jgFz8zhZ5tcrT5bxapPejhynVWlKuJFeohBb_uKfSlqktyyJzy5V7TBOgACwBxP4QHgAxUldx</recordid><startdate>19971031</startdate><enddate>19971031</enddate><creator>배춘일(Choon Il Bae)</creator><creator>공재명(Jae Myung Gong)</creator><creator>오정완(Jung Wan Oh)</creator><creator>김현종(Hyun Jong Kim)</creator><creator>오갑진(Gab Jin Oh)</creator><creator>박시경(Si Kyung Park)</creator><creator>정순간(Sun Gan Chung)</creator><creator>조의환(Eui Hwan Cho)</creator><general>The Pharmaceutical Society Of Korea</general><general>대한약학회</general><scope>P5Y</scope><scope>SSSTE</scope><scope>JDI</scope></search><sort><creationdate>19971031</creationdate><title>산오리나무의 세포독성 성분연구</title><author>배춘일(Choon Il Bae) ; 공재명(Jae Myung Gong) ; 오정완(Jung Wan Oh) ; 김현종(Hyun Jong Kim) ; 오갑진(Gab Jin Oh) ; 박시경(Si Kyung Park) ; 정순간(Sun Gan Chung) ; 조의환(Eui Hwan Cho)</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-k603-daea8b85ef28196103687faf47cf7030045288a231e72ba06b1ea10c09f31af93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>1997</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>배춘일(Choon Il Bae)</creatorcontrib><creatorcontrib>공재명(Jae Myung Gong)</creatorcontrib><creatorcontrib>오정완(Jung Wan Oh)</creatorcontrib><creatorcontrib>김현종(Hyun Jong Kim)</creatorcontrib><creatorcontrib>오갑진(Gab Jin Oh)</creatorcontrib><creatorcontrib>박시경(Si Kyung Park)</creatorcontrib><creatorcontrib>정순간(Sun Gan Chung)</creatorcontrib><creatorcontrib>조의환(Eui Hwan Cho)</creatorcontrib><collection>Kyobo Scholar (교보스콜라)</collection><collection>Scholar(스콜라)</collection><collection>KoreaScience</collection><jtitle>Yaghag-hoi-ji</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>배춘일(Choon Il Bae)</au><au>공재명(Jae Myung Gong)</au><au>오정완(Jung Wan Oh)</au><au>김현종(Hyun Jong Kim)</au><au>오갑진(Gab Jin Oh)</au><au>박시경(Si Kyung Park)</au><au>정순간(Sun Gan Chung)</au><au>조의환(Eui Hwan Cho)</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>산오리나무의 세포독성 성분연구</atitle><jtitle>Yaghag-hoi-ji</jtitle><addtitle>Yakhak hoeji</addtitle><date>1997-10-31</date><risdate>1997</risdate><volume>41</volume><issue>5</issue><spage>559</spage><epage>564</epage><pages>559-564</pages><issn>0377-9556</issn><eissn>2383-9457</eissn><abstract>To find out antitumor active principles from natural resources, we have evaluated various extracts from the leaves of Alnus hirsuta (Betulaceae). The ethylacetate extract of this plant was found to show a significant cytotoxicity against several kinds of cultured human solid tumor cell lines (AGS, A5 49, HCT15, SKOV3, HEP3B) in vitro. Using cytotoxicity-guided chromatographic purification of the ethylacetate extract, cytotoxic constituent:1,7-bis-(4-hydroxyphenyl)-5-(${\beta}$-D-glucopyranosyloxy)-3-heptanone, was isolated and structurally identified by physico-chemical properties and spectroscopic evidences.</abstract><pub>The Pharmaceutical Society Of Korea</pub><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0377-9556 |
| ispartof | Yaghag-hoi-ji, 1997-10, Vol.41 (5), p.559-564 |
| issn | 0377-9556 2383-9457 |
| language | kor |
| recordid | cdi_kisti_ndsl_JAKO199715875838696 |
| source | Alma/SFX Local Collection |
| title | 산오리나무의 세포독성 성분연구 |
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