Synthesis of 1-(Heterocyclic Substituted Anilino)-9H-Thioxanthon-9-ones and Their Antitumor Activity

Synthesis of 1-(Heterocyclic Substituted Anilino)-9H-Thioxanthon-9-ones and Their Antitumor Activity

Some new 9H-thioxanthen-9-one incorporated into heterocyclic systems such as pyridone 8, pyrazoline 9, pyranone 11, iminopyrane 12, furopyrimidine 17, imidazothiazole 19, thiazole 21, triazine 24 and other related compounds through a para imminophenyl grouping at position-1 of the thioxanthenone rin...

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Veröffentlicht in:Archives of pharmacal research 1997, Vol.20 (6), p.610-619
1. Verfasser: Omar, Mahmoud-T
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description Some new 9H-thioxanthen-9-one incorporated into heterocyclic systems such as pyridone 8, pyrazoline 9, pyranone 11, iminopyrane 12, furopyrimidine 17, imidazothiazole 19, thiazole 21, triazine 24 and other related compounds through a para imminophenyl grouping at position-1 of the thioxanthenone ring were synthesized and tested as antitumor agents against L1210 leukemia in mice. Some of the new compounds showed considerable antitumor activity.
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title Synthesis of 1-(Heterocyclic Substituted Anilino)-9H-Thioxanthon-9-ones and Their Antitumor Activity
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