지모(知母)의 항암활성성분에 관한 연구

지모(知母)의 항암활성성분에 관한 연구

EtOAc soluble part of MeOH extract of Anemarrhena asphodeloides rhizome was evaluated for the cytotoxicity against the five kinds of human tumor cell lines (A-549, SK-OV-3, SK-MEL-2, XF498 and HCT15) in vitro. Bioassay-guided fractionation of EtOAc soluble part led to the isolation of active compoun...

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Veröffentlicht in:생약학회지 1995, Vol.26 (1), p.47-50
Hauptverfasser: 이승호(Seung Ho Lee), 유시용(Shi Yong ryu), 최상운(sang Un Choi), 노재성(Zaesung No), 김성기(Sung Ki Kim), 이정옥(Chong Ock Lee), 안종웅(Jong Woong Ahn)
Format: Artikel
Sprache:kor
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Zusammenfassung:EtOAc soluble part of MeOH extract of Anemarrhena asphodeloides rhizome was evaluated for the cytotoxicity against the five kinds of human tumor cell lines (A-549, SK-OV-3, SK-MEL-2, XF498 and HCT15) in vitro. Bioassay-guided fractionation of EtOAc soluble part led to the isolation of active compound which was identified as timosaponin A-III showed potent cytotoxic activity, but its genin, sarsasapogenin, did not show cell growth inhibition.
ISSN:0253-3073
2288-9299