아출(莪朮)의 Sesquiterpene 성분의 약물활성
Pharmacological activities of two sesquiterpenes, curzerenone(I), and curcumenol(II) isolated from the rhizomes of Curcuma zedoaria being used as an aromatic stomachic in Chinese medicines were evaluated in rats and mice. Curzerenone (I), at 100mg/kg, p.o. showed a potent protective effect against H...
Gespeichert in:
| Veröffentlicht in: | 생약학회지 1994, Vol.25 (3), p.221-225 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | kor |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 225 |
|---|---|
| container_issue | 3 |
| container_start_page | 221 |
| container_title | 생약학회지 |
| container_volume | 25 |
| creator | 신국현 윤기영 조태순 Shin, Kuk-Hyun Yoon, Ki-Young Cho, Tae-Soon |
| description | Pharmacological activities of two sesquiterpenes, curzerenone(I), and curcumenol(II) isolated from the rhizomes of Curcuma zedoaria being used as an aromatic stomachic in Chinese medicines were evaluated in rats and mice. Curzerenone (I), at 100mg/kg, p.o. showed a potent protective effect against HCl-ethanol induced gastric lesion in rats, and curcumenol(II), at the same dose level showed a CNS depressant action characterized by a potentiation of hexobarbital(HB)-induced narcosis. Both compounds showed a moderate analgesic action but did not exhibit a hypothermic action even at 200mg/kg dose level. |
| format | Article |
| fullrecord | <record><control><sourceid>kisti</sourceid><recordid>TN_cdi_kisti_ndsl_JAKO199403041250038</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JAKO199403041250038</sourcerecordid><originalsourceid>FETCH-kisti_ndsl_JAKO1994030412500383</originalsourceid><addsrcrecordid>eNpjYeA0MDI11jU2MDfmYOAtLs5MMjAwMbK0MDM042QwezO15c22ORov-lY9m7NO883cGQrBqcWFpZklqUUFqXmpCm9aNr7e1gISfzN17-s1e97OnAMU4mFgTUvMKU7lhdLcDKpuriHOHrrZmcUlmfF5KcU58V6O3v6GlpYmBsYGJoZGpgYGxhbGxKoDAO2NP1c</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>아출(莪朮)의 Sesquiterpene 성분의 약물활성</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>신국현 ; 윤기영 ; 조태순 ; Shin, Kuk-Hyun ; Yoon, Ki-Young ; Cho, Tae-Soon</creator><creatorcontrib>신국현 ; 윤기영 ; 조태순 ; Shin, Kuk-Hyun ; Yoon, Ki-Young ; Cho, Tae-Soon</creatorcontrib><description>Pharmacological activities of two sesquiterpenes, curzerenone(I), and curcumenol(II) isolated from the rhizomes of Curcuma zedoaria being used as an aromatic stomachic in Chinese medicines were evaluated in rats and mice. Curzerenone (I), at 100mg/kg, p.o. showed a potent protective effect against HCl-ethanol induced gastric lesion in rats, and curcumenol(II), at the same dose level showed a CNS depressant action characterized by a potentiation of hexobarbital(HB)-induced narcosis. Both compounds showed a moderate analgesic action but did not exhibit a hypothermic action even at 200mg/kg dose level.</description><identifier>ISSN: 0253-3073</identifier><language>kor</language><ispartof>생약학회지, 1994, Vol.25 (3), p.221-225</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,4010</link.rule.ids></links><search><creatorcontrib>신국현</creatorcontrib><creatorcontrib>윤기영</creatorcontrib><creatorcontrib>조태순</creatorcontrib><creatorcontrib>Shin, Kuk-Hyun</creatorcontrib><creatorcontrib>Yoon, Ki-Young</creatorcontrib><creatorcontrib>Cho, Tae-Soon</creatorcontrib><title>아출(莪朮)의 Sesquiterpene 성분의 약물활성</title><title>생약학회지</title><addtitle>생약학회지</addtitle><description>Pharmacological activities of two sesquiterpenes, curzerenone(I), and curcumenol(II) isolated from the rhizomes of Curcuma zedoaria being used as an aromatic stomachic in Chinese medicines were evaluated in rats and mice. Curzerenone (I), at 100mg/kg, p.o. showed a potent protective effect against HCl-ethanol induced gastric lesion in rats, and curcumenol(II), at the same dose level showed a CNS depressant action characterized by a potentiation of hexobarbital(HB)-induced narcosis. Both compounds showed a moderate analgesic action but did not exhibit a hypothermic action even at 200mg/kg dose level.</description><issn>0253-3073</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>JDI</sourceid><recordid>eNpjYeA0MDI11jU2MDfmYOAtLs5MMjAwMbK0MDM042QwezO15c22ORov-lY9m7NO883cGQrBqcWFpZklqUUFqXmpCm9aNr7e1gISfzN17-s1e97OnAMU4mFgTUvMKU7lhdLcDKpuriHOHrrZmcUlmfF5KcU58V6O3v6GlpYmBsYGJoZGpgYGxhbGxKoDAO2NP1c</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>신국현</creator><creator>윤기영</creator><creator>조태순</creator><creator>Shin, Kuk-Hyun</creator><creator>Yoon, Ki-Young</creator><creator>Cho, Tae-Soon</creator><scope>JDI</scope></search><sort><creationdate>1994</creationdate><title>아출(莪朮)의 Sesquiterpene 성분의 약물활성</title><author>신국현 ; 윤기영 ; 조태순 ; Shin, Kuk-Hyun ; Yoon, Ki-Young ; Cho, Tae-Soon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-kisti_ndsl_JAKO1994030412500383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>1994</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>신국현</creatorcontrib><creatorcontrib>윤기영</creatorcontrib><creatorcontrib>조태순</creatorcontrib><creatorcontrib>Shin, Kuk-Hyun</creatorcontrib><creatorcontrib>Yoon, Ki-Young</creatorcontrib><creatorcontrib>Cho, Tae-Soon</creatorcontrib><collection>KoreaScience</collection><jtitle>생약학회지</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>신국현</au><au>윤기영</au><au>조태순</au><au>Shin, Kuk-Hyun</au><au>Yoon, Ki-Young</au><au>Cho, Tae-Soon</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>아출(莪朮)의 Sesquiterpene 성분의 약물활성</atitle><jtitle>생약학회지</jtitle><addtitle>생약학회지</addtitle><date>1994</date><risdate>1994</risdate><volume>25</volume><issue>3</issue><spage>221</spage><epage>225</epage><pages>221-225</pages><issn>0253-3073</issn><abstract>Pharmacological activities of two sesquiterpenes, curzerenone(I), and curcumenol(II) isolated from the rhizomes of Curcuma zedoaria being used as an aromatic stomachic in Chinese medicines were evaluated in rats and mice. Curzerenone (I), at 100mg/kg, p.o. showed a potent protective effect against HCl-ethanol induced gastric lesion in rats, and curcumenol(II), at the same dose level showed a CNS depressant action characterized by a potentiation of hexobarbital(HB)-induced narcosis. Both compounds showed a moderate analgesic action but did not exhibit a hypothermic action even at 200mg/kg dose level.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0253-3073 |
| ispartof | 생약학회지, 1994, Vol.25 (3), p.221-225 |
| issn | 0253-3073 |
| language | kor |
| recordid | cdi_kisti_ndsl_JAKO199403041250038 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| title | 아출(莪朮)의 Sesquiterpene 성분의 약물활성 |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T14%3A13%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-kisti&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=%EC%95%84%EC%B6%9C(%E8%8E%AA%E6%9C%AE)%EC%9D%98%20Sesquiterpene%20%EC%84%B1%EB%B6%84%EC%9D%98%20%EC%95%BD%EB%AC%BC%ED%99%9C%EC%84%B1&rft.jtitle=%EC%83%9D%EC%95%BD%ED%95%99%ED%9A%8C%EC%A7%80&rft.au=%EC%8B%A0%EA%B5%AD%ED%98%84&rft.date=1994&rft.volume=25&rft.issue=3&rft.spage=221&rft.epage=225&rft.pages=221-225&rft.issn=0253-3073&rft_id=info:doi/&rft_dat=%3Ckisti%3EJAKO199403041250038%3C/kisti%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |