헬리코박터 파일로리 감염과 호산구성 식도염의 연관성

Background/Aims: This study examined the association between eosinophilic esophagitis (EoE) and Helicobacter pylori (H. pylori) infection. Methods: A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003...

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Veröffentlicht in:The Korean journal of gastroenterology 2023-09, Vol.82 (3), p.122
Hauptverfasser: 장영훈, Young Hoon Chang, 신철민, Cheol Min Shin, 이동호, Dong Ho Lee, 윤혁, Hyuk Yoon, 박영수, Young Soo Park, 김나영, Nayoung Kim
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container_title The Korean journal of gastroenterology
container_volume 82
creator 장영훈
Young Hoon Chang
신철민
Cheol Min Shin
이동호
Dong Ho Lee
윤혁
Hyuk Yoon
박영수
Young Soo Park
김나영
Nayoung Kim
description Background/Aims: This study examined the association between eosinophilic esophagitis (EoE) and Helicobacter pylori (H. pylori) infection. Methods: A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003 to March 2022 were reviewed retrospectively. Forty-five EoE patients were included in the analysis. For each EoE patient, two age and sex-matched normal controls were selected randomly from an outpatient population who received upper gastrointestinal endoscopy. Results: Although 17 out of 90 (18.9%) controls had a H. pylori infection, only two out of 45 (4.4%) EoE patients showed evidence of a H. pylori infection. EoE was inversely associated with a H. pylori infection (odds ratio 0.20, 95% confidence interval 0.04-0.91, p=0.044). Conclusions: An inverse association was observed between H. pylori infection and EoE. Further prospective studies will be needed to validate the protective effects of H. pylori infection for EoE. (Korean J Gastroenterol 2023;82:122-126)
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Methods: A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003 to March 2022 were reviewed retrospectively. Forty-five EoE patients were included in the analysis. For each EoE patient, two age and sex-matched normal controls were selected randomly from an outpatient population who received upper gastrointestinal endoscopy. Results: Although 17 out of 90 (18.9%) controls had a H. pylori infection, only two out of 45 (4.4%) EoE patients showed evidence of a H. pylori infection. EoE was inversely associated with a H. pylori infection (odds ratio 0.20, 95% confidence interval 0.04-0.91, p=0.044). Conclusions: An inverse association was observed between H. pylori infection and EoE. Further prospective studies will be needed to validate the protective effects of H. pylori infection for EoE. 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source KoreaMed Synapse; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; KoreaMed Open Access
subjects Eosinophilic esophagitis
Helicobacter pylori
Hygiene hypothesis
title 헬리코박터 파일로리 감염과 호산구성 식도염의 연관성
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