헬리코박터 파일로리 감염과 호산구성 식도염의 연관성
Background/Aims: This study examined the association between eosinophilic esophagitis (EoE) and Helicobacter pylori (H. pylori) infection. Methods: A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003...
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Veröffentlicht in: | The Korean journal of gastroenterology 2023-09, Vol.82 (3), p.122 |
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container_title | The Korean journal of gastroenterology |
container_volume | 82 |
creator | 장영훈 Young Hoon Chang 신철민 Cheol Min Shin 이동호 Dong Ho Lee 윤혁 Hyuk Yoon 박영수 Young Soo Park 김나영 Nayoung Kim |
description | Background/Aims: This study examined the association between eosinophilic esophagitis (EoE) and Helicobacter pylori (H. pylori) infection.
Methods: A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003 to March 2022 were reviewed retrospectively. Forty-five EoE patients were included in the analysis. For each EoE patient, two age and sex-matched normal controls were selected randomly from an outpatient population who received upper gastrointestinal endoscopy.
Results: Although 17 out of 90 (18.9%) controls had a H. pylori infection, only two out of 45 (4.4%) EoE patients showed evidence of a H. pylori infection. EoE was inversely associated with a H. pylori infection (odds ratio 0.20, 95% confidence interval 0.04-0.91, p=0.044).
Conclusions: An inverse association was observed between H. pylori infection and EoE. Further prospective studies will be needed to validate the protective effects of H. pylori infection for EoE. (Korean J Gastroenterol 2023;82:122-126) |
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Methods: A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003 to March 2022 were reviewed retrospectively. Forty-five EoE patients were included in the analysis. For each EoE patient, two age and sex-matched normal controls were selected randomly from an outpatient population who received upper gastrointestinal endoscopy.
Results: Although 17 out of 90 (18.9%) controls had a H. pylori infection, only two out of 45 (4.4%) EoE patients showed evidence of a H. pylori infection. EoE was inversely associated with a H. pylori infection (odds ratio 0.20, 95% confidence interval 0.04-0.91, p=0.044).
Conclusions: An inverse association was observed between H. pylori infection and EoE. Further prospective studies will be needed to validate the protective effects of H. pylori infection for EoE. (Korean J Gastroenterol 2023;82:122-126)</description><identifier>ISSN: 1598-9992</identifier><language>kor</language><publisher>대한소화기학회</publisher><subject>Eosinophilic esophagitis ; Helicobacter pylori ; Hygiene hypothesis</subject><ispartof>The Korean journal of gastroenterology, 2023-09, Vol.82 (3), p.122</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782</link.rule.ids></links><search><creatorcontrib>장영훈</creatorcontrib><creatorcontrib>Young Hoon Chang</creatorcontrib><creatorcontrib>신철민</creatorcontrib><creatorcontrib>Cheol Min Shin</creatorcontrib><creatorcontrib>이동호</creatorcontrib><creatorcontrib>Dong Ho Lee</creatorcontrib><creatorcontrib>윤혁</creatorcontrib><creatorcontrib>Hyuk Yoon</creatorcontrib><creatorcontrib>박영수</creatorcontrib><creatorcontrib>Young Soo Park</creatorcontrib><creatorcontrib>김나영</creatorcontrib><creatorcontrib>Nayoung Kim</creatorcontrib><title>헬리코박터 파일로리 감염과 호산구성 식도염의 연관성</title><title>The Korean journal of gastroenterology</title><addtitle>대한소화기학회지</addtitle><description>Background/Aims: This study examined the association between eosinophilic esophagitis (EoE) and Helicobacter pylori (H. pylori) infection.
Methods: A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003 to March 2022 were reviewed retrospectively. Forty-five EoE patients were included in the analysis. For each EoE patient, two age and sex-matched normal controls were selected randomly from an outpatient population who received upper gastrointestinal endoscopy.
Results: Although 17 out of 90 (18.9%) controls had a H. pylori infection, only two out of 45 (4.4%) EoE patients showed evidence of a H. pylori infection. EoE was inversely associated with a H. pylori infection (odds ratio 0.20, 95% confidence interval 0.04-0.91, p=0.044).
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Methods: A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003 to March 2022 were reviewed retrospectively. Forty-five EoE patients were included in the analysis. For each EoE patient, two age and sex-matched normal controls were selected randomly from an outpatient population who received upper gastrointestinal endoscopy.
Results: Although 17 out of 90 (18.9%) controls had a H. pylori infection, only two out of 45 (4.4%) EoE patients showed evidence of a H. pylori infection. EoE was inversely associated with a H. pylori infection (odds ratio 0.20, 95% confidence interval 0.04-0.91, p=0.044).
Conclusions: An inverse association was observed between H. pylori infection and EoE. Further prospective studies will be needed to validate the protective effects of H. pylori infection for EoE. (Korean J Gastroenterol 2023;82:122-126)</abstract><pub>대한소화기학회</pub><tpages>5</tpages></addata></record> |
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source | KoreaMed Synapse; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; KoreaMed Open Access |
subjects | Eosinophilic esophagitis Helicobacter pylori Hygiene hypothesis |
title | 헬리코박터 파일로리 감염과 호산구성 식도염의 연관성 |
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