Hepatocellular carcinoma incidence is decreasing in Korea but increasing in the very elderly
Background/Aims: A comprehensive analysis of trends in the incidence of hepatocellular carcinoma (HCC) is important for planning public health initiatives. We aimed to analyze the trends in HCC incidence in South Korea over 10 years and to predict the incidence for the year 2028. Methods: Data from...
Gespeichert in:
| Veröffentlicht in: | Clinical and molecular hepatology 2023-01, Vol.29 (1), p.120 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | kor |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 1 |
| container_start_page | 120 |
| container_title | Clinical and molecular hepatology |
| container_volume | 29 |
| creator | Young Eun Chon Seong Yong Park Han Pyo Hong Donghee Son Jonghyun Lee Eileen Yoon Soon Sun Kim Sang Bong Ahn Soung Won Jeong Dae Won Jun |
| description | Background/Aims: A comprehensive analysis of trends in the incidence of hepatocellular carcinoma (HCC) is important for planning public health initiatives. We aimed to analyze the trends in HCC incidence in South Korea over 10 years and to predict the incidence for the year 2028.
Methods: Data from patients with newly diagnosed HCC between 2008 and 2018 were obtained from Korean National Health Insurance Service database. Age-standardized incidence rates (ASRs) were calculated to compare HCC incidence. A poisson regression model was used to predict the future incidence of HCC.
Results: The average crude incidence rate (CR) was 22.4 per 100,000 person-years, and the average ASR was 17.6 per 100,000 person-years between 2008 and 2018. The CR (from 23.9 to 21.2 per 100,000 person-years) and ASR (from 21.9 to 14.3 per 100,000 person-years) of HCC incidence decreased during the past ten years in all age groups, except in the elderly. The ASR of patients aged ≥80 years increased significantly (from 70.0 to 160.2/100,000 person-years; average annual percent change, +9.00%; P |
| format | Article |
| fullrecord | <record><control><sourceid>kiss</sourceid><recordid>TN_cdi_kiss_primary_4002822</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><kiss_id>4002822</kiss_id><sourcerecordid>4002822</sourcerecordid><originalsourceid>FETCH-kiss_primary_40028223</originalsourceid><addsrcrecordid>eNp9isEKgkAURWdRkJRf0Ob9gGDPCd1HIbRtGchzfNWjcZQZDfz7DFq0anW4556FihCLPMEci5WKQ5A61TrPsp3eR-pack9DZ9ja0ZIHQ96I61oCcUYadoZBAjRsPFMQd589nLt5QD0On-jHDw-GF_sJ2Dbs7bRRyxvZwPGXa7U9HS-HMnlKCFXvpSU_VTpNsUDM_r9v6C8-Kw</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Hepatocellular carcinoma incidence is decreasing in Korea but increasing in the very elderly</title><source>ProQuest One Community College</source><source>KoreaMed Synapse</source><source>ProQuest Central (Alumni Edition)</source><source>PubMed Central Open Access</source><source>KoreaMed Open Access</source><source>ProQuest Central UK/Ireland</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>DOAJ开放获取期刊资源库</source><source>ProQuest Central</source><creator>Young Eun Chon ; Seong Yong Park ; Han Pyo Hong ; Donghee Son ; Jonghyun Lee ; Eileen Yoon ; Soon Sun Kim ; Sang Bong Ahn ; Soung Won Jeong ; Dae Won Jun</creator><creatorcontrib>Young Eun Chon ; Seong Yong Park ; Han Pyo Hong ; Donghee Son ; Jonghyun Lee ; Eileen Yoon ; Soon Sun Kim ; Sang Bong Ahn ; Soung Won Jeong ; Dae Won Jun</creatorcontrib><description>Background/Aims: A comprehensive analysis of trends in the incidence of hepatocellular carcinoma (HCC) is important for planning public health initiatives. We aimed to analyze the trends in HCC incidence in South Korea over 10 years and to predict the incidence for the year 2028.
Methods: Data from patients with newly diagnosed HCC between 2008 and 2018 were obtained from Korean National Health Insurance Service database. Age-standardized incidence rates (ASRs) were calculated to compare HCC incidence. A poisson regression model was used to predict the future incidence of HCC.
Results: The average crude incidence rate (CR) was 22.4 per 100,000 person-years, and the average ASR was 17.6 per 100,000 person-years between 2008 and 2018. The CR (from 23.9 to 21.2 per 100,000 person-years) and ASR (from 21.9 to 14.3 per 100,000 person-years) of HCC incidence decreased during the past ten years in all age groups, except in the elderly. The ASR of patients aged ≥80 years increased significantly (from 70.0 to 160.2/100,000 person-years; average annual percent change, +9.00%; P<0.001). The estimated CR (17.9 per 100,000 person-years) and ASR (9.7 per 100,000 person-years) of HCC incidence in 2028 was declined, but the number of HCC patients aged ≥80 years in 2028 will be quadruple greater than the number of HCC patients in 2008 (from 521 to 2,055), comprising 21.3% of all HCC patients in 2028.
Conclusions: The ASRs of HCC in Korea have gradually declined over the past 10 years, but the number, CR, and ASR are increasing in patients aged ≥80 years. (Clin Mol Hepatol 2023;29:120-134)</description><identifier>ISSN: 2287-2728</identifier><language>kor</language><publisher>대한간학회</publisher><subject>Age-standardized incidence rate ; Hepatocellular carcinoma ; Incidence ; Korea ; Prediction</subject><ispartof>Clinical and molecular hepatology, 2023-01, Vol.29 (1), p.120</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Young Eun Chon</creatorcontrib><creatorcontrib>Seong Yong Park</creatorcontrib><creatorcontrib>Han Pyo Hong</creatorcontrib><creatorcontrib>Donghee Son</creatorcontrib><creatorcontrib>Jonghyun Lee</creatorcontrib><creatorcontrib>Eileen Yoon</creatorcontrib><creatorcontrib>Soon Sun Kim</creatorcontrib><creatorcontrib>Sang Bong Ahn</creatorcontrib><creatorcontrib>Soung Won Jeong</creatorcontrib><creatorcontrib>Dae Won Jun</creatorcontrib><title>Hepatocellular carcinoma incidence is decreasing in Korea but increasing in the very elderly</title><title>Clinical and molecular hepatology</title><addtitle>Clinical and Molecular Hepatology(대한간학회지)</addtitle><description>Background/Aims: A comprehensive analysis of trends in the incidence of hepatocellular carcinoma (HCC) is important for planning public health initiatives. We aimed to analyze the trends in HCC incidence in South Korea over 10 years and to predict the incidence for the year 2028.
Methods: Data from patients with newly diagnosed HCC between 2008 and 2018 were obtained from Korean National Health Insurance Service database. Age-standardized incidence rates (ASRs) were calculated to compare HCC incidence. A poisson regression model was used to predict the future incidence of HCC.
Results: The average crude incidence rate (CR) was 22.4 per 100,000 person-years, and the average ASR was 17.6 per 100,000 person-years between 2008 and 2018. The CR (from 23.9 to 21.2 per 100,000 person-years) and ASR (from 21.9 to 14.3 per 100,000 person-years) of HCC incidence decreased during the past ten years in all age groups, except in the elderly. The ASR of patients aged ≥80 years increased significantly (from 70.0 to 160.2/100,000 person-years; average annual percent change, +9.00%; P<0.001). The estimated CR (17.9 per 100,000 person-years) and ASR (9.7 per 100,000 person-years) of HCC incidence in 2028 was declined, but the number of HCC patients aged ≥80 years in 2028 will be quadruple greater than the number of HCC patients in 2008 (from 521 to 2,055), comprising 21.3% of all HCC patients in 2028.
Conclusions: The ASRs of HCC in Korea have gradually declined over the past 10 years, but the number, CR, and ASR are increasing in patients aged ≥80 years. (Clin Mol Hepatol 2023;29:120-134)</description><subject>Age-standardized incidence rate</subject><subject>Hepatocellular carcinoma</subject><subject>Incidence</subject><subject>Korea</subject><subject>Prediction</subject><issn>2287-2728</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9isEKgkAURWdRkJRf0Ob9gGDPCd1HIbRtGchzfNWjcZQZDfz7DFq0anW4556FihCLPMEci5WKQ5A61TrPsp3eR-pack9DZ9ja0ZIHQ96I61oCcUYadoZBAjRsPFMQd589nLt5QD0On-jHDw-GF_sJ2Dbs7bRRyxvZwPGXa7U9HS-HMnlKCFXvpSU_VTpNsUDM_r9v6C8-Kw</recordid><startdate>20230101</startdate><enddate>20230101</enddate><creator>Young Eun Chon</creator><creator>Seong Yong Park</creator><creator>Han Pyo Hong</creator><creator>Donghee Son</creator><creator>Jonghyun Lee</creator><creator>Eileen Yoon</creator><creator>Soon Sun Kim</creator><creator>Sang Bong Ahn</creator><creator>Soung Won Jeong</creator><creator>Dae Won Jun</creator><general>대한간학회</general><scope>HZB</scope><scope>Q5X</scope></search><sort><creationdate>20230101</creationdate><title>Hepatocellular carcinoma incidence is decreasing in Korea but increasing in the very elderly</title><author>Young Eun Chon ; Seong Yong Park ; Han Pyo Hong ; Donghee Son ; Jonghyun Lee ; Eileen Yoon ; Soon Sun Kim ; Sang Bong Ahn ; Soung Won Jeong ; Dae Won Jun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-kiss_primary_40028223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>2023</creationdate><topic>Age-standardized incidence rate</topic><topic>Hepatocellular carcinoma</topic><topic>Incidence</topic><topic>Korea</topic><topic>Prediction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Young Eun Chon</creatorcontrib><creatorcontrib>Seong Yong Park</creatorcontrib><creatorcontrib>Han Pyo Hong</creatorcontrib><creatorcontrib>Donghee Son</creatorcontrib><creatorcontrib>Jonghyun Lee</creatorcontrib><creatorcontrib>Eileen Yoon</creatorcontrib><creatorcontrib>Soon Sun Kim</creatorcontrib><creatorcontrib>Sang Bong Ahn</creatorcontrib><creatorcontrib>Soung Won Jeong</creatorcontrib><creatorcontrib>Dae Won Jun</creatorcontrib><collection>Korean Studies Information Service System (KISS)</collection><collection>Korean Studies Information Service System (KISS) B-Type</collection><jtitle>Clinical and molecular hepatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Young Eun Chon</au><au>Seong Yong Park</au><au>Han Pyo Hong</au><au>Donghee Son</au><au>Jonghyun Lee</au><au>Eileen Yoon</au><au>Soon Sun Kim</au><au>Sang Bong Ahn</au><au>Soung Won Jeong</au><au>Dae Won Jun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hepatocellular carcinoma incidence is decreasing in Korea but increasing in the very elderly</atitle><jtitle>Clinical and molecular hepatology</jtitle><addtitle>Clinical and Molecular Hepatology(대한간학회지)</addtitle><date>2023-01-01</date><risdate>2023</risdate><volume>29</volume><issue>1</issue><spage>120</spage><pages>120-</pages><issn>2287-2728</issn><abstract>Background/Aims: A comprehensive analysis of trends in the incidence of hepatocellular carcinoma (HCC) is important for planning public health initiatives. We aimed to analyze the trends in HCC incidence in South Korea over 10 years and to predict the incidence for the year 2028.
Methods: Data from patients with newly diagnosed HCC between 2008 and 2018 were obtained from Korean National Health Insurance Service database. Age-standardized incidence rates (ASRs) were calculated to compare HCC incidence. A poisson regression model was used to predict the future incidence of HCC.
Results: The average crude incidence rate (CR) was 22.4 per 100,000 person-years, and the average ASR was 17.6 per 100,000 person-years between 2008 and 2018. The CR (from 23.9 to 21.2 per 100,000 person-years) and ASR (from 21.9 to 14.3 per 100,000 person-years) of HCC incidence decreased during the past ten years in all age groups, except in the elderly. The ASR of patients aged ≥80 years increased significantly (from 70.0 to 160.2/100,000 person-years; average annual percent change, +9.00%; P<0.001). The estimated CR (17.9 per 100,000 person-years) and ASR (9.7 per 100,000 person-years) of HCC incidence in 2028 was declined, but the number of HCC patients aged ≥80 years in 2028 will be quadruple greater than the number of HCC patients in 2008 (from 521 to 2,055), comprising 21.3% of all HCC patients in 2028.
Conclusions: The ASRs of HCC in Korea have gradually declined over the past 10 years, but the number, CR, and ASR are increasing in patients aged ≥80 years. (Clin Mol Hepatol 2023;29:120-134)</abstract><pub>대한간학회</pub><tpages>15</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2287-2728 |
| ispartof | Clinical and molecular hepatology, 2023-01, Vol.29 (1), p.120 |
| issn | 2287-2728 |
| language | kor |
| recordid | cdi_kiss_primary_4002822 |
| source | ProQuest One Community College; KoreaMed Synapse; ProQuest Central (Alumni Edition); PubMed Central Open Access; KoreaMed Open Access; ProQuest Central UK/Ireland; PubMed Central; Alma/SFX Local Collection; DOAJ开放获取期刊资源库; ProQuest Central |
| subjects | Age-standardized incidence rate Hepatocellular carcinoma Incidence Korea Prediction |
| title | Hepatocellular carcinoma incidence is decreasing in Korea but increasing in the very elderly |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T04%3A13%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-kiss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Hepatocellular%20carcinoma%20incidence%20is%20decreasing%20in%20Korea%20but%20increasing%20in%20the%20very%20elderly&rft.jtitle=Clinical%20and%20molecular%20hepatology&rft.au=Young%20Eun%20Chon&rft.date=2023-01-01&rft.volume=29&rft.issue=1&rft.spage=120&rft.pages=120-&rft.issn=2287-2728&rft_id=info:doi/&rft_dat=%3Ckiss%3E4002822%3C/kiss%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_kiss_id=4002822&rfr_iscdi=true |