The Effects of PPAR Agonists on Atherosclerosis and Nonalcoholic Fatty Liver Disease in ApoE -/- FXR -/- Mice

Background: Farnesoid X receptor (FXR), a bile acid-activated nuclear receptor, is a potent regulator of glucose and lipid metabolism as well as of bile acid metabolism. Previous studies have demonstrated that FXR deficiency is associated with metabolic derangements, including atherosclerosis and no...

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Veröffentlicht in:Endocrinology and metabolism (Seoul) 2021-12, Vol.36 (6), p.1243
Hauptverfasser: Yenna Lee, Bo-rahm Kim, Geun-hyung Kang, Gwan Jae Lee, Young Joo Park, Haeryoung Kim, Hak Chul Jang, Sung Hee Choi
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