파국적 항인지질항체증후군과 관련된 소장의 괴사 1예

Catastrophic antiphospholipid syndrome is a highly fatal condition characterized by widespread thromboembolism subsequent to a triggering factor (e.g., infection, trauma, and neoplasia) in antiphospholipid antibody-positive patients. This paper reports a case of a 29-year-old male without the underl...

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Veröffentlicht in:The Korean journal of gastroenterology 2021-06, Vol.77 (6), p.294
Hauptverfasser: 이현애, Hyun Ae Lee, 김성은, Seong-eun Kim, 정도영, Do Woung Jung, 변주란, Ju Ran Byeon, 최아름, A Reum Choe, 태정현, Chung Hyun Tae, 문창모, Chang Mo Moon, 정혜경, Hye Kyung Jung, 심기남, Ki Nam Shim, 정성애, Sung Ae Jung
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Zusammenfassung:Catastrophic antiphospholipid syndrome is a highly fatal condition characterized by widespread thromboembolism subsequent to a triggering factor (e.g., infection, trauma, and neoplasia) in antiphospholipid antibody-positive patients. This paper reports a case of a 29-year-old male without the underlying disease who developed extensive mesenteric thromboembolism and jejunal necrosis during the treatment for acute enteritis. The patient’s condition was improved with low-molecular-weight heparin and an intravenous Ig treatment with emergency surgery. The serum antiphospholipid (anticardiolipin IgM) and lupus anticoagulant antibody tests showed positive results. Acute infectious enterocolitis is generally considered a mild disease. On the other hand, aggressive evaluation and treatment should be considered if the clinical conditions do not improve and deteriorate rapidly despite appropriate antibiotic treatment because of the possibility of acute immunological complications, such as catastrophic antiphospholipid syndrome. (Korean J Gastroenterol 2021;77:294-299)
ISSN:1598-9992