Palisaded Neutrophilic and Granulomatous Dermatitis in a Patient with Behçet’s Disease: A Case Report

Palisaded Neutrophilic and Granulomatous Dermatitis in a Patient with Behçet’s Disease: A Case Report

Palisaded neutrophilic and granulomatous dermatitis (PNGD) is an uncommon skin eruption and characterized histopatho-logically by the presence of granulomatous inflammation with or without leukocytoclastic vasculitis. PNGD is known to be associated with various immune-mediated connective tissue dise...

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Veröffentlicht in:Annals of dermatology 2021-02, Vol.33 (1), p.73
Hauptverfasser: Young-bin Shin, Jeong-won Jo, Tae-jin Yoon
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Behcet syndrome
Palisaded neutrophilic granulomatous dermatitis
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Jeong-won Jo
Tae-jin Yoon
description Palisaded neutrophilic and granulomatous dermatitis (PNGD) is an uncommon skin eruption and characterized histopatho-logically by the presence of granulomatous inflammation with or without leukocytoclastic vasculitis. PNGD is known to be associated with various immune-mediated connective tissue diseases such as rheumatoid arthritis and lupus erythematosus. However, to our knowledge, a case of PNGD in a patient with Behçet’s disease is extremely rare and only one case has been reported in foreign literature to date. Herein, we report an unusual case of a 60-year-old female with Behçet’s disease who presented multiple erythematous to flesh-colored papules on the extremities, buttocks, and ear lobes and was diagnosed with PNGD. After the treatment of systemic corticosteroids, colchicine and azathioprine, the skin lesions and oral ulcers improved. The patient is under observation without recurrence of skin lesions for 6 months. (Ann Dermatol 33(1) 73∼76, 2021)
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subjects Behcet syndrome
Palisaded neutrophilic granulomatous dermatitis
title Palisaded Neutrophilic and Granulomatous Dermatitis in a Patient with Behçet’s Disease: A Case Report
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