Nrf2-Heme oxygenase-1 modulates autophagy and inhibits apoptosis triggered by elevated glucose levels in renal tubule cells

Background: Autophagy is a highly balanced process in which lysosomes remove aged and damaged organelles and cellular proteins. Autophagy is essential to maintain homeostasis in the kidneys. Methods: Using human renal tubule cells HK-2, we assessed the impact of high glucose (HG) on autophagy. We al...

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Veröffentlicht in:	Kidney research and clinical practice 2019-09, Vol.38 (3), p.318
Hauptverfasser:	Joo-heon Kim, Kyeong Min Kim, Jin Uk Jeong, Jong Ho Shin, Jae Min Shin, Ki Tae Bang
Format:	Artikel
Sprache:	kor
Schlagworte:	Autophagy Diabetic nephropathies Heme oxygenase-1 Nrf2 Sulforaphane
Online-Zugang:	Volltext
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