The Significance of NOTCH Pathway in the Development of Fibrosis in Systemic Sclerosis

Systemic sclerosis (SSc) is an autoimmune disorder characterized by the fibrosis of skin, heart, lung, and kidney as well. Excessive activation of fibroblasts is associated with higher expression of Notch1 and/or Notch3 genes. The constitutive expression of NOTCH genes was described in epithelial ce...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Annals of dermatology 2019-08, Vol.31 (4), p.365
Hauptverfasser:	Szymon Zmorzynski, Wojciech Styk, Agata Anna Filip, Dorota Krasowska
Format:	Artikel
Sprache:	kor
Schlagworte:	Fibrosis NOTCH genes NOTCH pathway Scleroderma systemic Transforming growth factor beta
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!