Changes in the Expression and Distribution of Claudins, Increased Epithelial Apoptosis, and a Mannan-Binding Lectin-Associated Immune Response Lead to Barrier Dysfunction in Dextran Sodium Sulfate-Induced Rat Colitis

Background/Aims: This animal study aimed to define the underlying cellular mechanisms of intestinal barrier dysfunction. Methods: Rats were fed 4% with dextran sodium sulfate (DSS) to induce experimental colitis. We analyzed the sugars in 24-hour urine output by high pressure liquid chromatography....

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Veröffentlicht in:	Gut and liver 2015-11, Vol.9 (6), p.734
Hauptverfasser:	Bosi Yuan, Shuping Zhou, Youke Lu, Jiong Liu, Xinxin Jin, Haijun Wan, Fangyu Wang
Format:	Artikel
Sprache:	kor
Schlagworte:	Apoptosis Claudin Colitis Intestinal permeability Mannan-binding lectin-associated serine proteases 2 ulcerative
Online-Zugang:	Volltext
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