Clinical Utility of Plasma Glypican-3 and Osteopontin as Biomarkers of Hepatocellular Carcinoma

Background/Aims: α-Fetoprotein (AFP) is the biomarkermost widely used to detect hepatocellular carcinoma (HCC),despite its suboptimal diagnostic accuracy. Glypican-3 (GPC3)and osteopontin (OPN) are secreted glycoproteins that are reportedlyassociated with tumorigenesis and metastasis. Thisstudy was...

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Veröffentlicht in:Gut and liver 2014-03, Vol.8 (2), p.177
Hauptverfasser: Hyun Jung Lee, Jong Eun Yeon, Sang Jun Suh, Sun Jae Lee, Eileen L Yoon, Keun Hee Kang, Yang Jae Yoo, Ji Hoon Kim, Yeon Seok Seo, Hyung Joon Yim, Kwan Soo Byun
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