Imatinib 치료 후 수술로 제거된 바터씨 팽대부의 악성 위장관간질종양

Imatinib 치료 후 수술로 제거된 바터씨 팽대부의 악성 위장관간질종양

Gastrointestinal stromal tumor (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract arising from Cajal`s cells, expressing CD 117. The standard treatment for primary GIST is complete surgical resection. Imatinib mesylate, a specific tyrosine kinase inhibitor, is effective aga...

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Veröffentlicht in:The Korean journal of gastroenterology 2010-07, Vol.56 (1), p.39
Hauptverfasser: 박정은, Jeung Eun Park, 동석호, Seok Ho Dong, 조근형, Kun Hyung Cho, 장재영, Jae Young Jang, 김효종, Hyo Jong Kim, 김병호, Byung Ho Kim, 장영운, Young Woon Chang, 장린, Rin Chang
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Ampulla of Vater
Gastrointestinal stromal tumor
Imatinib
Surgery
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container_issue 1
container_start_page 39
container_title The Korean journal of gastroenterology
container_volume 56
creator 박정은
Jeung Eun Park
동석호
Seok Ho Dong
조근형
Kun Hyung Cho
장재영
Jae Young Jang
김효종
Hyo Jong Kim
김병호
Byung Ho Kim
장영운
Young Woon Chang
장린
Rin Chang
description Gastrointestinal stromal tumor (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract arising from Cajal`s cells, expressing CD 117. The standard treatment for primary GIST is complete surgical resection. Imatinib mesylate, a specific tyrosine kinase inhibitor, is effective against locally advanced and metastatic GIST. There are several reports of the effect of preoperative imatinib in patients with unresectable and locally advanced primary GIST. We report a case of unresectable primary GIST of the ampulla of Vater, which we were able to completely resect after treatment with a dosage of imatinib 400 mg daily for 5 months. Twelve months later, the patient was treated with imatinib and doing well with no evidence of recurrence. (Korean J Gastroenterol 2010;56:39-44)
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source KoreaMed Synapse; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; KoreaMed Open Access
subjects Ampulla of Vater
Gastrointestinal stromal tumor
Imatinib
Surgery
title Imatinib 치료 후 수술로 제거된 바터씨 팽대부의 악성 위장관간질종양
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