트리클로로에틸렌의 직업적 노출에 의한 과민성 박탈 피부염 및 간염

A 20-year-old man was admitted to the hospital because of pruritus, pyrexia and maculopapular skin rash. Three weeks before admission, he engaged in silicon waterproofing work with trichloroethylene (TCE). The levels of liver enzymes increased and exfoliative dermatitis was developed on the trunk an...

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Veröffentlicht in:Chʻŏnsik mit alrerugi 2009-06, Vol.29 (2), p.132
Hauptverfasser: 하재화, Jae Hwa Ha, 이철갑, Chul Gab Lee, 윤성호, Sung Ho Yoon, 이승일, Seung Il Lee, 권용은, Yong Eun Kwon
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container_issue 2
container_start_page 132
container_title Chʻŏnsik mit alrerugi
container_volume 29
creator 하재화
Jae Hwa Ha
이철갑
Chul Gab Lee
윤성호
Sung Ho Yoon
이승일
Seung Il Lee
권용은
Yong Eun Kwon
description A 20-year-old man was admitted to the hospital because of pruritus, pyrexia and maculopapular skin rash. Three weeks before admission, he engaged in silicon waterproofing work with trichloroethylene (TCE). The levels of liver enzymes increased and exfoliative dermatitis was developed on the trunk and face. After treatment with systemic corticosteroids, antihistamine and liver supplements, liver function and skin lesions were improved remarkably. The levels of serum IgE increased and the pathological examination of skin specimen revealed T lymphocyte-mediated inflammatory reaction. Since other causes could not be found through the multiple allergen simultaneous test (MAST) and other allergy tests, we assumed that exfoliative dermatitis and hepatitis were caused by T lymphocyte hypersensitivity to TCE, which was confirmed by the patch test after his symptoms were improved. (Korean J Asthma Allergy Clin Immunol 2009;29:132-137)
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Three weeks before admission, he engaged in silicon waterproofing work with trichloroethylene (TCE). The levels of liver enzymes increased and exfoliative dermatitis was developed on the trunk and face. After treatment with systemic corticosteroids, antihistamine and liver supplements, liver function and skin lesions were improved remarkably. The levels of serum IgE increased and the pathological examination of skin specimen revealed T lymphocyte-mediated inflammatory reaction. Since other causes could not be found through the multiple allergen simultaneous test (MAST) and other allergy tests, we assumed that exfoliative dermatitis and hepatitis were caused by T lymphocyte hypersensitivity to TCE, which was confirmed by the patch test after his symptoms were improved. 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identifier ISSN: 1226-8739
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source KoreaMed Open Access
subjects Delayed hypersensitivity
Exfoliative dermatitis
Hepatitis
Occupational exposure
Trichloroethylene
title 트리클로로에틸렌의 직업적 노출에 의한 과민성 박탈 피부염 및 간염
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