Nitric Oxide Synthesis in the Adult and Developing Kidney
Nitric oxide (NO) is synthesized within the adult and developing kidney and plays a critical role in the regulation of renal hemodynamics and tubule function. In the adult kidney, the regulation of NO synthesis is very cell type specific and subject to distinct control mechanisms of NO synthase (NOS...
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| Veröffentlicht in: | Electrolyte & blood pressure : E & BP 2006-03, Vol.4 (1), p.1 |
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| creator | Ki Hwan Han Ju Young Jung Ku Yong Chung Hyang Kim Jin Kim |
| description | Nitric oxide (NO) is synthesized within the adult and developing kidney and plays a critical role in the regulation of renal hemodynamics and tubule function. In the adult kidney, the regulation of NO synthesis is very cell type specific and subject to distinct control mechanisms of NO synthase (NOS) isoforms. Endothelial NOS (eNOS) is expressed in the endothelial cells of glomeruli, peritubular capillaries, and vascular bundles. Neuronal NOS (nNOS) is expressed in the tubular epithelial cells of the macula densa and inner medullary collecting duct. Furthermore, in the immature kidney, the expression of eNOS and nNOS shows unique patterns distinct from that is observed in the adult. This review will summarize the localization and presumable function of NOS isoforms in the adult and developing kidney. |
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In the adult kidney, the regulation of NO synthesis is very cell type specific and subject to distinct control mechanisms of NO synthase (NOS) isoforms. Endothelial NOS (eNOS) is expressed in the endothelial cells of glomeruli, peritubular capillaries, and vascular bundles. Neuronal NOS (nNOS) is expressed in the tubular epithelial cells of the macula densa and inner medullary collecting duct. Furthermore, in the immature kidney, the expression of eNOS and nNOS shows unique patterns distinct from that is observed in the adult. This review will summarize the localization and presumable function of NOS isoforms in the adult and developing kidney.</description><identifier>ISSN: 1738-5997</identifier><identifier>EISSN: 2092-9935</identifier><language>kor</language><publisher>대한전해질학회</publisher><subject>Development ; Kidney ; Nitric oxide ; Renal hemodynamics</subject><ispartof>Electrolyte & blood pressure : E & BP, 2006-03, Vol.4 (1), p.1</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785</link.rule.ids></links><search><creatorcontrib>Ki Hwan Han</creatorcontrib><creatorcontrib>Ju Young Jung</creatorcontrib><creatorcontrib>Ku Yong Chung</creatorcontrib><creatorcontrib>Hyang Kim</creatorcontrib><creatorcontrib>Jin Kim</creatorcontrib><title>Nitric Oxide Synthesis in the Adult and Developing Kidney</title><title>Electrolyte & blood pressure : E & BP</title><addtitle>Electrolytes & Blood Pressure</addtitle><description>Nitric oxide (NO) is synthesized within the adult and developing kidney and plays a critical role in the regulation of renal hemodynamics and tubule function. 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This review will summarize the localization and presumable function of NOS isoforms in the adult and developing kidney.</description><subject>Development</subject><subject>Kidney</subject><subject>Nitric oxide</subject><subject>Renal hemodynamics</subject><issn>1738-5997</issn><issn>2092-9935</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNpjYuA0MrA00rW0NDZlYeA0NDe20DW1tDTnYOAtLs4yAAITCwNzSxNOBku_zJKizGQF_4rMlFSF4Mq8kozU4sxihcw8BSBLwTGlNKdEITEvRcEltSw1J78gMy9dwTszJS-1koeBNS0xpziVF0pzM0i7uYY4e-hmZxYXxxcUZeYmFlXGG5kaGlsamhjjlwUANCsyNw</recordid><startdate>20060310</startdate><enddate>20060310</enddate><creator>Ki Hwan Han</creator><creator>Ju Young Jung</creator><creator>Ku Yong Chung</creator><creator>Hyang Kim</creator><creator>Jin Kim</creator><general>대한전해질학회</general><scope>HZB</scope><scope>Q5X</scope></search><sort><creationdate>20060310</creationdate><title>Nitric Oxide Synthesis in the Adult and Developing Kidney</title><author>Ki Hwan Han ; Ju Young Jung ; Ku Yong Chung ; Hyang Kim ; Jin Kim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-kiss_primary_25139143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>2006</creationdate><topic>Development</topic><topic>Kidney</topic><topic>Nitric oxide</topic><topic>Renal hemodynamics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ki Hwan Han</creatorcontrib><creatorcontrib>Ju Young Jung</creatorcontrib><creatorcontrib>Ku Yong Chung</creatorcontrib><creatorcontrib>Hyang Kim</creatorcontrib><creatorcontrib>Jin Kim</creatorcontrib><collection>Korean Studies Information Service System (KISS)</collection><collection>Korean Studies Information Service System (KISS) B-Type</collection><jtitle>Electrolyte & blood pressure : E & BP</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ki Hwan Han</au><au>Ju Young Jung</au><au>Ku Yong Chung</au><au>Hyang Kim</au><au>Jin Kim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nitric Oxide Synthesis in the Adult and Developing Kidney</atitle><jtitle>Electrolyte & blood pressure : E & BP</jtitle><addtitle>Electrolytes & Blood Pressure</addtitle><date>2006-03-10</date><risdate>2006</risdate><volume>4</volume><issue>1</issue><spage>1</spage><pages>1-</pages><issn>1738-5997</issn><eissn>2092-9935</eissn><abstract>Nitric oxide (NO) is synthesized within the adult and developing kidney and plays a critical role in the regulation of renal hemodynamics and tubule function. In the adult kidney, the regulation of NO synthesis is very cell type specific and subject to distinct control mechanisms of NO synthase (NOS) isoforms. Endothelial NOS (eNOS) is expressed in the endothelial cells of glomeruli, peritubular capillaries, and vascular bundles. Neuronal NOS (nNOS) is expressed in the tubular epithelial cells of the macula densa and inner medullary collecting duct. Furthermore, in the immature kidney, the expression of eNOS and nNOS shows unique patterns distinct from that is observed in the adult. This review will summarize the localization and presumable function of NOS isoforms in the adult and developing kidney.</abstract><pub>대한전해질학회</pub><tpages>7</tpages></addata></record> |
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| issn | 1738-5997 2092-9935 |
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| source | KoreaMed Synapse; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central |
| subjects | Development Kidney Nitric oxide Renal hemodynamics |
| title | Nitric Oxide Synthesis in the Adult and Developing Kidney |
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