고혈압환자에서 도플러 심초음파를 이용한 좌우심실 이완기능에 관한 연구

Background: It is well known that the diastolic dysfunction of the left ventricle plays an important role in pathophysiology of heart failure in the various cardiac diseases. And many hypertensive patients manifest diastolic dysfunction of the left ventricle in its early stage. But, there are very few studies of right ventricular diastolic dysfunction reported, and effects of systemic hypertension on right ventricular function are not well understood. Thus, left ventricular diastolic dysfunction and its effects to right ventricular function need to be evaluated in hypertensive patients. Method: For the evaluation of the left and right ventricuiar diastolic function in the hypertensive patients, 20 normotensive control subjects and 30 untreated essential hypertensive patients were studied by pulsed doppler echocardiography at the left and right ventricular inflow, and then E/A velocity ratio [E/A (v)], acceleration time (AT), deceleration time (DT), and diastolic filling period (DFP) were measured after confirming normal ejection fraction by M-mode echocardiography. Results: 1) In the 20 normal control group, ejection fraction was 63.7±11.8% and in the 30 hypertensive patient group, it was 60.3±10.8%. There was no significant differences between the normal control and the hypertensive patient group. 2) In the normal control group, E/A (v) of left ventricle was 1. 48±0.32, E/A (v) of LV was 0.88±1.07, mean E/A (v) of RV was 0.91±0.73. E/A (v) of LV & RV was significantly decreased (p