간경변증 환자에서 위내 적색반과 혈청 Pepsinogen 1 치에 관한 연구

Background: Gastric mucosal lesions in chronic liver diseases are uncommon. However, the pathogenesis and mechanism of gastric mucosal lesions are unclear. To investigate the cause of gastric red spots (Mucosal vascular ectasia), we measured fasting serum pepsinogen I level. Method: To investgate the secretory function of gastric mucosa in liver cirrhosis and the causes of gastric red spots, we measured fasting serum pepsinogen. I. Forty-one subjects were studied: ten with liver cirrhosis showing endoscopic gastric red spots, sixteen with liver cirrhosis not showing gastric lesions, and twenty-five normal controls. Result: In control groups, the results showed higher levels of serum pepsinogen I in smokers than in nonsmokers. Serum Pepsinogen I levels were significantly lower in cirrhotic patients than normal control groups (73.64±4.65ng/ml vs, 118.85±5.45ng/ml: p