양측성 원발성 부신 비호즈킨 림프종 1 예

저자들은 65세 남자환자에서 만성 C형 간염으로 외래추적검사중 우연히 양측성 부신종괴를 발견하고 개복 생검하여 B세포 미만성 대세포형 림프종으로 진단하고, 비장절제술과 좌측 부신제거술과 CHOP 복합화학요법 3회 시행 후 추적 전산화단층촬영상 부신종괴는 사라졌으나 점차 심해지는 전신쇠약감으로 대증치료를 하던 중 패혈증이 합병되어 진단 4개월만에 사망한 원발성 부신 림프종을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Primary adrenal lymphoma is extremely rare with only 65 cases reported in the worldwide literature until 1998. The presenting symptom may be related to the lymphoma itself or to adrenal insufficiency. Most of the lymphomas were of B cell diffuse large cell type with only two seemed to be T-cell in origin. The therapeutic modalities include surgery, combination chemotherapy, surgery followed by chemotherapy and/or radiation therapy, in addition to corticosteroid replacement. A 65 year old man with chronic hepatitis C and hemangioma of liver presented with general weakness. Abdominal ultrasonography showed bilateral adrenal masses. The adrenal masses were diagnosed as a primary adrenal non-Hodgkin's lymphoma by open biopsy. The histologic findings were consistent with B cell diffuse large cell lymphoma. After three cycles of CHOP chemotherapy, the adrenal mass disappeared on follow up abdominal CT scan, but the patient died 4 months after diagnosis due to sepsis.(Korean J Med 59:447-451, 2000)