Vecuronium 분할투여에 의한 기관내삽관의 임상적 평가
In the clinical situations which the use of SCC for endotracheal incubation is contraindi-cated, we have currently tried to find semi ideal substitutes for SCC. One of these, neuromuscular blockade will occur sooner if the intubating dose of a non-depolarizing drug is proceded by a small, subparalyz...
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| Veröffentlicht in: | Korean journal of anesthesiology 1987-07, Vol.20 (4), p.456 |
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| creator | 조정현 Chung Hyun Cho 김원옥 Won Oak Kim 박광원 Kwang Won Park 신양식 Yang Sik Shin 김혜란 Hae Ran Kim |
| description | In the clinical situations which the use of SCC for endotracheal incubation is contraindi-cated, we have currently tried to find semi ideal substitutes for SCC. One of these, neuromuscular blockade will occur sooner if the intubating dose of a non-depolarizing drug is proceded by a small, subparalyzing initial dose. Our previous studs for the divided doses of pancuronium was concluded to be a substi-
tute for SCC. However, the slow onset and long duration of pancuronium were net suita-ble in some clinical applications. This study was undertaken to eatimate a newer shorter acting relaxant, vecuronium, in divided doses to apply for rapid sequence endotracheal intubation. The subparalyzing dose, 0.01 mg/kg, of vencuronium 4 min. prior to its intubating dose, 0.1 mg/kg, for all patients was administered under the monitoring of TOF response with Relaxograph. The intubating dose of vecuronium followed immediately the induction agent, thiopental sodium (5 mg/kg) . Orotracheal intubation was done 90 sec after the intubating dose. Intubation conditions and TOF responses were evaluated. The results are as follows : 1 ) After the priming dose, twenty-six patients complained of minor aide effects. 2) There was no difficultly in intubation. Forty·mix patients(94%) were distributed in 1 and 2 grade of intubation condition. 3) In the grade 1, female patients were more distrihuted than male patients(p |
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tute for SCC. However, the slow onset and long duration of pancuronium were net suita-ble in some clinical applications. This study was undertaken to eatimate a newer shorter acting relaxant, vecuronium, in divided doses to apply for rapid sequence endotracheal intubation. The subparalyzing dose, 0.01 mg/kg, of vencuronium 4 min. prior to its intubating dose, 0.1 mg/kg, for all patients was administered under the monitoring of TOF response with Relaxograph. The intubating dose of vecuronium followed immediately the induction agent, thiopental sodium (5 mg/kg) . Orotracheal intubation was done 90 sec after the intubating dose. Intubation conditions and TOF responses were evaluated. The results are as follows : 1 ) After the priming dose, twenty-six patients complained of minor aide effects. 2) There was no difficultly in intubation. Forty·mix patients(94%) were distributed in 1 and 2 grade of intubation condition. 3) In the grade 1, female patients were more distrihuted than male patients(p<0.05) . 4) The responses of TOF at the intubation were 44.54±38,92%. There were wide indivi-dual variances. 5) The internal between the intubating dose and the disappeared twitch response was 3.72±2.73 min. The first twitch reappeared 26.04±10.86 min. after the intubating dose.
In conclusion, we recommend that the divited doses of vecuronium(the priming and int-ubating doses, 0.01 mg/kg and 7.1 mg/kg, respectively) for the rapid sequence endotracheal intubation may be applied adequately in some clinical situations.</description><identifier>ISSN: 2005-6419</identifier><identifier>EISSN: 2005-7563</identifier><language>kor</language><publisher>대한마취통증의학회(구 대한마취과학회)</publisher><ispartof>Korean journal of anesthesiology, 1987-07, Vol.20 (4), p.456</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785</link.rule.ids></links><search><creatorcontrib>조정현</creatorcontrib><creatorcontrib>Chung Hyun Cho</creatorcontrib><creatorcontrib>김원옥</creatorcontrib><creatorcontrib>Won Oak Kim</creatorcontrib><creatorcontrib>박광원</creatorcontrib><creatorcontrib>Kwang Won Park</creatorcontrib><creatorcontrib>신양식</creatorcontrib><creatorcontrib>Yang Sik Shin</creatorcontrib><creatorcontrib>김혜란</creatorcontrib><creatorcontrib>Hae Ran Kim</creatorcontrib><title>Vecuronium 분할투여에 의한 기관내삽관의 임상적 평가</title><title>Korean journal of anesthesiology</title><addtitle>Korean Journal of Anesthesiology(구 대한마취과학회지)</addtitle><description>In the clinical situations which the use of SCC for endotracheal incubation is contraindi-cated, we have currently tried to find semi ideal substitutes for SCC. One of these, neuromuscular blockade will occur sooner if the intubating dose of a non-depolarizing drug is proceded by a small, subparalyzing initial dose. Our previous studs for the divided doses of pancuronium was concluded to be a substi-
tute for SCC. However, the slow onset and long duration of pancuronium were net suita-ble in some clinical applications. This study was undertaken to eatimate a newer shorter acting relaxant, vecuronium, in divided doses to apply for rapid sequence endotracheal intubation. The subparalyzing dose, 0.01 mg/kg, of vencuronium 4 min. prior to its intubating dose, 0.1 mg/kg, for all patients was administered under the monitoring of TOF response with Relaxograph. The intubating dose of vecuronium followed immediately the induction agent, thiopental sodium (5 mg/kg) . Orotracheal intubation was done 90 sec after the intubating dose. Intubation conditions and TOF responses were evaluated. The results are as follows : 1 ) After the priming dose, twenty-six patients complained of minor aide effects. 2) There was no difficultly in intubation. Forty·mix patients(94%) were distributed in 1 and 2 grade of intubation condition. 3) In the grade 1, female patients were more distrihuted than male patients(p<0.05) . 4) The responses of TOF at the intubation were 44.54±38,92%. There were wide indivi-dual variances. 5) The internal between the intubating dose and the disappeared twitch response was 3.72±2.73 min. The first twitch reappeared 26.04±10.86 min. after the intubating dose.
In conclusion, we recommend that the divited doses of vecuronium(the priming and int-ubating doses, 0.01 mg/kg and 7.1 mg/kg, respectively) for the rapid sequence endotracheal intubation may be applied adequately in some clinical situations.</description><issn>2005-6419</issn><issn>2005-7563</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><recordid>eNpjYuA0MjAw1TU3NTNmgbLNTAwtORh4i4szkwxMDcyNTcwtjDgZXMNSk0uL8vMyS3MVXm9reTt1wduONW-mA9EEhTdzZ7ydOkfh1Y4Nr7Y0vG7a8qZpL5ABFFV4M6_lTXPjmwWNCm_7O19taOBhYE1LzClO5YXS3Awhbq4hzh66Pv7uns6OPrrZJkbmuqnJ5oYpxkCLU41NDMwszAySTYxSUo2MUpINLBJTjNPSUlOMko0SLVOMDFOTUi0Nkw2TLCxSLVPMDE0MDC2NDI25GaQhxmZnFhfHFxRl5iYWVcYbWlgYmZkZGAMAp7JWrA</recordid><startdate>19870730</startdate><enddate>19870730</enddate><creator>조정현</creator><creator>Chung Hyun Cho</creator><creator>김원옥</creator><creator>Won Oak Kim</creator><creator>박광원</creator><creator>Kwang Won Park</creator><creator>신양식</creator><creator>Yang Sik Shin</creator><creator>김혜란</creator><creator>Hae Ran Kim</creator><general>대한마취통증의학회(구 대한마취과학회)</general><scope>HZB</scope><scope>Q5X</scope></search><sort><creationdate>19870730</creationdate><title>Vecuronium 분할투여에 의한 기관내삽관의 임상적 평가</title><author>조정현 ; Chung Hyun Cho ; 김원옥 ; Won Oak Kim ; 박광원 ; Kwang Won Park ; 신양식 ; Yang Sik Shin ; 김혜란 ; Hae Ran Kim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-k427-ec71d3347e3406860c42de22dc08ad3ffed2c2a9d21ebe91c1b88e9d614019213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>1987</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>조정현</creatorcontrib><creatorcontrib>Chung Hyun Cho</creatorcontrib><creatorcontrib>김원옥</creatorcontrib><creatorcontrib>Won Oak Kim</creatorcontrib><creatorcontrib>박광원</creatorcontrib><creatorcontrib>Kwang Won Park</creatorcontrib><creatorcontrib>신양식</creatorcontrib><creatorcontrib>Yang Sik Shin</creatorcontrib><creatorcontrib>김혜란</creatorcontrib><creatorcontrib>Hae Ran Kim</creatorcontrib><collection>Korean Studies Information Service System (KISS)</collection><collection>Korean Studies Information Service System (KISS) B-Type</collection><jtitle>Korean journal of anesthesiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>조정현</au><au>Chung Hyun Cho</au><au>김원옥</au><au>Won Oak Kim</au><au>박광원</au><au>Kwang Won Park</au><au>신양식</au><au>Yang Sik Shin</au><au>김혜란</au><au>Hae Ran Kim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vecuronium 분할투여에 의한 기관내삽관의 임상적 평가</atitle><jtitle>Korean journal of anesthesiology</jtitle><addtitle>Korean Journal of Anesthesiology(구 대한마취과학회지)</addtitle><date>1987-07-30</date><risdate>1987</risdate><volume>20</volume><issue>4</issue><spage>456</spage><pages>456-</pages><issn>2005-6419</issn><eissn>2005-7563</eissn><abstract>In the clinical situations which the use of SCC for endotracheal incubation is contraindi-cated, we have currently tried to find semi ideal substitutes for SCC. One of these, neuromuscular blockade will occur sooner if the intubating dose of a non-depolarizing drug is proceded by a small, subparalyzing initial dose. Our previous studs for the divided doses of pancuronium was concluded to be a substi-
tute for SCC. However, the slow onset and long duration of pancuronium were net suita-ble in some clinical applications. This study was undertaken to eatimate a newer shorter acting relaxant, vecuronium, in divided doses to apply for rapid sequence endotracheal intubation. The subparalyzing dose, 0.01 mg/kg, of vencuronium 4 min. prior to its intubating dose, 0.1 mg/kg, for all patients was administered under the monitoring of TOF response with Relaxograph. The intubating dose of vecuronium followed immediately the induction agent, thiopental sodium (5 mg/kg) . Orotracheal intubation was done 90 sec after the intubating dose. Intubation conditions and TOF responses were evaluated. The results are as follows : 1 ) After the priming dose, twenty-six patients complained of minor aide effects. 2) There was no difficultly in intubation. Forty·mix patients(94%) were distributed in 1 and 2 grade of intubation condition. 3) In the grade 1, female patients were more distrihuted than male patients(p<0.05) . 4) The responses of TOF at the intubation were 44.54±38,92%. There were wide indivi-dual variances. 5) The internal between the intubating dose and the disappeared twitch response was 3.72±2.73 min. The first twitch reappeared 26.04±10.86 min. after the intubating dose.
In conclusion, we recommend that the divited doses of vecuronium(the priming and int-ubating doses, 0.01 mg/kg and 7.1 mg/kg, respectively) for the rapid sequence endotracheal intubation may be applied adequately in some clinical situations.</abstract><pub>대한마취통증의학회(구 대한마취과학회)</pub><tpages>6</tpages></addata></record> |
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| title | Vecuronium 분할투여에 의한 기관내삽관의 임상적 평가 |
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