Fentanyl 정주에 의한 기침유발과 Lidocaine 의 기침억제효과
Background: Cough suppression is a well-known side effect of all opioid analgesics, but we experienced cough response after small dose of intravenous fentanyl. The goal of this study was to demonstrate the tussive effect of intravenous fentanyl. Method: 311 patients(ASA class 1, 2) were assigned ran...
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| Veröffentlicht in: | Korean journal of anesthesiology 1996-10, Vol.31 (4), p.462 |
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| container_title | Korean journal of anesthesiology |
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| creator | 이귀용 Guie Yong Lee 한종인 Jong In Han 이춘희 Choon Hi Lee 오은정 Eun Jung Oh |
| description | Background: Cough suppression is a well-known side effect of all opioid analgesics, but we experienced cough response after small dose of intravenous fentanyl. The goal of this study was to demonstrate the tussive effect of intravenous fentanyl. Method: 311 patients(ASA class 1, 2) were assigned randomly into three groups. Patient in group 1 recieved fentanyl 1 ug/kg, patients in group 2 were given fentanyl 2 ug/kg, and patients in group 3 recieved fentanyl 2 ug/kg 2 min after lidocaine 1 mg/kg. We observed for 1 min after fentanyl injection to detect a cough response. Results: Tussive response of fentanyl is produced by low dose (1-2 ug/kg) fentanyl IV, and decreased by lidocaine pretreatment. This response is decreased with aging. All event is not related bronchospasm and anticholinergic premedication. Conclusion: We concluded that fentanyl causes tussive response and this response is inhibited by lidocaine and decreased with aging. (Korean J Anesthesiol 1996; 31: 462~465) |
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The goal of this study was to demonstrate the tussive effect of intravenous fentanyl. Method: 311 patients(ASA class 1, 2) were assigned randomly into three groups. Patient in group 1 recieved fentanyl 1 ug/kg, patients in group 2 were given fentanyl 2 ug/kg, and patients in group 3 recieved fentanyl 2 ug/kg 2 min after lidocaine 1 mg/kg. We observed for 1 min after fentanyl injection to detect a cough response. Results: Tussive response of fentanyl is produced by low dose (1-2 ug/kg) fentanyl IV, and decreased by lidocaine pretreatment. This response is decreased with aging. All event is not related bronchospasm and anticholinergic premedication. Conclusion: We concluded that fentanyl causes tussive response and this response is inhibited by lidocaine and decreased with aging. (Korean J Anesthesiol 1996; 31: 462~465)</description><identifier>ISSN: 2005-6419</identifier><identifier>EISSN: 2005-7563</identifier><language>kor</language><publisher>대한마취통증의학회(구 대한마취과학회)</publisher><subject>Anesthetics ; cough ; fentanyl. Complication ; intravenous</subject><ispartof>Korean journal of anesthesiology, 1996-10, Vol.31 (4), p.462</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>이귀용</creatorcontrib><creatorcontrib>Guie Yong Lee</creatorcontrib><creatorcontrib>한종인</creatorcontrib><creatorcontrib>Jong In Han</creatorcontrib><creatorcontrib>이춘희</creatorcontrib><creatorcontrib>Choon Hi Lee</creatorcontrib><creatorcontrib>오은정</creatorcontrib><creatorcontrib>Eun Jung Oh</creatorcontrib><title>Fentanyl 정주에 의한 기침유발과 Lidocaine 의 기침억제효과</title><title>Korean journal of anesthesiology</title><addtitle>Korean Journal of Anesthesiology(구 대한마취과학회지)</addtitle><description>Background: Cough suppression is a well-known side effect of all opioid analgesics, but we experienced cough response after small dose of intravenous fentanyl. The goal of this study was to demonstrate the tussive effect of intravenous fentanyl. Method: 311 patients(ASA class 1, 2) were assigned randomly into three groups. Patient in group 1 recieved fentanyl 1 ug/kg, patients in group 2 were given fentanyl 2 ug/kg, and patients in group 3 recieved fentanyl 2 ug/kg 2 min after lidocaine 1 mg/kg. We observed for 1 min after fentanyl injection to detect a cough response. Results: Tussive response of fentanyl is produced by low dose (1-2 ug/kg) fentanyl IV, and decreased by lidocaine pretreatment. This response is decreased with aging. All event is not related bronchospasm and anticholinergic premedication. Conclusion: We concluded that fentanyl causes tussive response and this response is inhibited by lidocaine and decreased with aging. (Korean J Anesthesiol 1996; 31: 462~465)</description><subject>Anesthetics</subject><subject>cough</subject><subject>fentanyl. 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The goal of this study was to demonstrate the tussive effect of intravenous fentanyl. Method: 311 patients(ASA class 1, 2) were assigned randomly into three groups. Patient in group 1 recieved fentanyl 1 ug/kg, patients in group 2 were given fentanyl 2 ug/kg, and patients in group 3 recieved fentanyl 2 ug/kg 2 min after lidocaine 1 mg/kg. We observed for 1 min after fentanyl injection to detect a cough response. Results: Tussive response of fentanyl is produced by low dose (1-2 ug/kg) fentanyl IV, and decreased by lidocaine pretreatment. This response is decreased with aging. All event is not related bronchospasm and anticholinergic premedication. Conclusion: We concluded that fentanyl causes tussive response and this response is inhibited by lidocaine and decreased with aging. (Korean J Anesthesiol 1996; 31: 462~465)</abstract><pub>대한마취통증의학회(구 대한마취과학회)</pub><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2005-6419 |
| ispartof | Korean journal of anesthesiology, 1996-10, Vol.31 (4), p.462 |
| issn | 2005-6419 2005-7563 |
| language | kor |
| recordid | cdi_kiss_primary_1882175 |
| source | DOAJ Directory of Open Access Journals |
| subjects | Anesthetics cough fentanyl. Complication intravenous |
| title | Fentanyl 정주에 의한 기침유발과 Lidocaine 의 기침억제효과 |
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