Clonidine 경구 투여가 기관내 삽관시 심혈관계에 미치는 효과
Induction of general anesthesia with tracheal intubation is routine proeedure but causes varying degrees of sympathetic stimulation such as increases in blood pressure and heart rate. Many approaches have been tried to attenuate these hemodynamic responses To evaluate the effects of clonidine, a-2 a...
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| Veröffentlicht in: | Korean journal of anesthesiology 1992-06, Vol.25 (3), p.571 |
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| container_title | Korean journal of anesthesiology |
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| creator | 황재현 Jai Hyun Hwang 최종무 Jong Moo Choi 조성강 Seong Kang Cho |
| description | Induction of general anesthesia with tracheal intubation is routine proeedure but causes varying degrees of sympathetic stimulation such as increases in blood pressure and heart rate. Many approaches have been tried to attenuate these hemodynamic responses To evaluate the effects of clonidine, a-2 adrenergic receptor agonist, on the hemodynamic changes induced by intubation, we administered clonidine(5 ug/kg, P.O.) 90 minutes before induction of anesthesia. We measured systolic pressure, diastolic pressure and heart rate before premedication, before induction, after intubation and 5, 10 minutes after intubation and compared with control group. The results were as follows: 1) After intubation systolic and diastolic blood pressures increased significantly in both group(P |
| format | Article |
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Many approaches have been tried to attenuate these hemodynamic responses To evaluate the effects of clonidine, a-2 adrenergic receptor agonist, on the hemodynamic changes induced by intubation, we administered clonidine(5 ug/kg, P.O.) 90 minutes before induction of anesthesia. We measured systolic pressure, diastolic pressure and heart rate before premedication, before induction, after intubation and 5, 10 minutes after intubation and compared with control group. The results were as follows: 1) After intubation systolic and diastolic blood pressures increased significantly in both group(P<0.05) but the increasing rate was significantly less than in clonidine group. (P<0.05) 2) After intubation the increaae in heart rate in clonidine group was significantly less than in control group (p<0.05). 3) The trend of increase in heart rate in clonidine group was more stabilized than control group. 4) Systolic blood pressure and heart rate in clonidine group were significantly decreased in preinduction period after premedication.</description><identifier>ISSN: 2005-6419</identifier><language>kor</language><publisher>대한마취통증의학회</publisher><subject>Hemodynamics ; Intubation ; Oral clonidine</subject><ispartof>Korean journal of anesthesiology, 1992-06, Vol.25 (3), p.571</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>황재현</creatorcontrib><creatorcontrib>Jai Hyun Hwang</creatorcontrib><creatorcontrib>최종무</creatorcontrib><creatorcontrib>Jong Moo Choi</creatorcontrib><creatorcontrib>조성강</creatorcontrib><creatorcontrib>Seong Kang Cho</creatorcontrib><title>Clonidine 경구 투여가 기관내 삽관시 심혈관계에 미치는 효과</title><title>Korean journal of anesthesiology</title><addtitle>Korean Journal of Anesthesiology</addtitle><description>Induction of general anesthesia with tracheal intubation is routine proeedure but causes varying degrees of sympathetic stimulation such as increases in blood pressure and heart rate. 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(P<0.05) 2) After intubation the increaae in heart rate in clonidine group was significantly less than in control group (p<0.05). 3) The trend of increase in heart rate in clonidine group was more stabilized than control group. 4) Systolic blood pressure and heart rate in clonidine group were significantly decreased in preinduction period after premedication.</description><subject>Hemodynamics</subject><subject>Intubation</subject><subject>Oral clonidine</subject><issn>2005-6419</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><recordid>eNpjYeA0MjAw1TUzMbTkYOAtLs5MMjA1MDc2Mbcw4mTwd87Jz8tMycxLVXi1ae-rrWsU3naseTN9zasNDQqvdmx4taXhddMWhTdNe4GsN91zFN50r3k7owPIebW55c30CQqv1-94s3PG664pCm9nrXi1eQ8PA2taYk5xKi-U5mYIcXMNcfbQ9fF393R29NHNNjGy1E1KNU5MM0sFOcPYINnQ0DLZyDDVMNXc0sjSxDzF3Dg5ydLI0MjUJNEwKS3RzMTAxDTRONnE1NAgKSUlMS3F2JibQRpibHZmcXF8QVFmbmJRZbyhhYWhsYWxMQCs4Fvb</recordid><startdate>19920630</startdate><enddate>19920630</enddate><creator>황재현</creator><creator>Jai Hyun Hwang</creator><creator>최종무</creator><creator>Jong Moo Choi</creator><creator>조성강</creator><creator>Seong Kang Cho</creator><general>대한마취통증의학회</general><scope>HZB</scope><scope>Q5X</scope></search><sort><creationdate>19920630</creationdate><title>Clonidine 경구 투여가 기관내 삽관시 심혈관계에 미치는 효과</title><author>황재현 ; Jai Hyun Hwang ; 최종무 ; Jong Moo Choi ; 조성강 ; Seong Kang Cho</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-k429-be3af6e507330c119c21e1e792947d73cb921254a1bfa64045a3c4510bddafd33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>1992</creationdate><topic>Hemodynamics</topic><topic>Intubation</topic><topic>Oral clonidine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>황재현</creatorcontrib><creatorcontrib>Jai Hyun Hwang</creatorcontrib><creatorcontrib>최종무</creatorcontrib><creatorcontrib>Jong Moo Choi</creatorcontrib><creatorcontrib>조성강</creatorcontrib><creatorcontrib>Seong Kang Cho</creatorcontrib><collection>Korean Studies Information Service System (KISS)</collection><collection>Korean Studies Information Service System (KISS) B-Type</collection><jtitle>Korean journal of anesthesiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>황재현</au><au>Jai Hyun Hwang</au><au>최종무</au><au>Jong Moo Choi</au><au>조성강</au><au>Seong Kang Cho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clonidine 경구 투여가 기관내 삽관시 심혈관계에 미치는 효과</atitle><jtitle>Korean journal of anesthesiology</jtitle><addtitle>Korean Journal of Anesthesiology</addtitle><date>1992-06-30</date><risdate>1992</risdate><volume>25</volume><issue>3</issue><spage>571</spage><pages>571-</pages><issn>2005-6419</issn><abstract>Induction of general anesthesia with tracheal intubation is routine proeedure but causes varying degrees of sympathetic stimulation such as increases in blood pressure and heart rate. Many approaches have been tried to attenuate these hemodynamic responses To evaluate the effects of clonidine, a-2 adrenergic receptor agonist, on the hemodynamic changes induced by intubation, we administered clonidine(5 ug/kg, P.O.) 90 minutes before induction of anesthesia. We measured systolic pressure, diastolic pressure and heart rate before premedication, before induction, after intubation and 5, 10 minutes after intubation and compared with control group. The results were as follows: 1) After intubation systolic and diastolic blood pressures increased significantly in both group(P<0.05) but the increasing rate was significantly less than in clonidine group. (P<0.05) 2) After intubation the increaae in heart rate in clonidine group was significantly less than in control group (p<0.05). 3) The trend of increase in heart rate in clonidine group was more stabilized than control group. 4) Systolic blood pressure and heart rate in clonidine group were significantly decreased in preinduction period after premedication.</abstract><pub>대한마취통증의학회</pub><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2005-6419 |
| ispartof | Korean journal of anesthesiology, 1992-06, Vol.25 (3), p.571 |
| issn | 2005-6419 |
| language | kor |
| recordid | cdi_kiss_primary_1881383 |
| source | DOAJ Directory of Open Access Journals |
| subjects | Hemodynamics Intubation Oral clonidine |
| title | Clonidine 경구 투여가 기관내 삽관시 심혈관계에 미치는 효과 |
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