위점막탈출증 환자에서의 식도내압검사 소견

Background/Aims: The purpose of this study was to investigate the roles of the abnormalities of lower esophageal sphincter (LES) and esophageal body as a factor of gastric mucosal prolapse (GMP). Methods: Ninety-one patients were classified into the GMP group (n=51) and control group (n=40). They ha...

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Veröffentlicht in:The Korean journal of gastroenterology 1999-01, Vol.34 (4), p.431
Hauptverfasser: 이준성, Joon Seong Lee, 천갑진, Gab Jin Chun, 홍수진, Su Jin Hong, 문종호, Jong Ho Moon, 김진오, Jin Oh Kim, 조영덕, Young Deok Cho, 조주영, Joo Young Cho, 이문성, Moon Sung Lee, 심찬섭, Chan Sup Shim
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container_issue 4
container_start_page 431
container_title The Korean journal of gastroenterology
container_volume 34
creator 이준성
Joon Seong Lee
천갑진
Gab Jin Chun
홍수진
Su Jin Hong
문종호
Jong Ho Moon
김진오
Jin Oh Kim
조영덕
Young Deok Cho
조주영
Joo Young Cho
이문성
Moon Sung Lee
심찬섭
Chan Sup Shim
description Background/Aims: The purpose of this study was to investigate the roles of the abnormalities of lower esophageal sphincter (LES) and esophageal body as a factor of gastric mucosal prolapse (GMP). Methods: Ninety-one patients were classified into the GMP group (n=51) and control group (n=40). They had a routine esophageal manometry. Fourteen patients of GMP group and 18 normal controls had a dynamic study to assess the effect of routine endoscopic premedication such as atropine sulfate and scopolamine butylbromide. Results: The mean pressure of LES in GMP group was similar to that in the control group (22.99±9.97 mmHg vs 25.46±7.92 mmHg). LES length of the GMP group was shorter than that of the control group (3.33±0.73 mm vs 3.88±0.78 mm, p
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Methods: Ninety-one patients were classified into the GMP group (n=51) and control group (n=40). They had a routine esophageal manometry. Fourteen patients of GMP group and 18 normal controls had a dynamic study to assess the effect of routine endoscopic premedication such as atropine sulfate and scopolamine butylbromide. Results: The mean pressure of LES in GMP group was similar to that in the control group (22.99±9.97 mmHg vs 25.46±7.92 mmHg). LES length of the GMP group was shorter than that of the control group (3.33±0.73 mm vs 3.88±0.78 mm, p&lt;0.05), but errors in measurement should be considered. Other parameters such as mean amplitude, duration and velocity of the peristaltic waves in esophageal body were not different in the both groups. By the findings of endoscopy and manometry, GMP was accompanied by redundant gastric mucosa of fundus or upper body (51/51), hiatal hernia (9/51), nutcracker esophagus (2/51), hypertensive LES (1/51) and nonspecific esophageal motor disturbance (NEMD) (5/51). In the dynamic study, the mean basal pressures of LES were significantly decreased after premedication in both groups (p&lt;0.05), and the percentage of pressure reduction in both groups was similar (71.93±6.16% vs 73.56±10.61%). Conclusions: The pathogenesis of the gastric mucosal prolapse was not associated with a decrease of LES pressure and sensitivity for premedication. It may be caused mainly by redundancy of gastric mucosa, and partially by hiatal hernia. 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source DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Endoscopy
Esophageal manometry
Gastric mucosal prolapse
title 위점막탈출증 환자에서의 식도내압검사 소견
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