부산 및 경남지역에서의 원발성 위장관 임파종의 임상적 고찰

A total of 492 patients admitted to Kosin Medical Center from 1970 to 1985 with lymphoma were reviewed for gastrointestinal involvement. Primary involvement was found in 42 cases whose incidence was 8.5%. Of all lymphoma observed during the same period. There was no particular age predominance and male to female ratio was 2:l. The commonest initial presenting symptom was abdominal pain(90.5%), abdominal mass (42.9%) and dyspepsia(33.3%) in order. The sites of involvement were the stomach in 13 cases(31.0%), the ileum in 14 cases(33.3%), the jejunum in 4 cases(9.5%), the ileocecal area in 17 cases(40.5%) and the large intestine in 12(26.2%). By the histological classification by Rappaport method in 42 cases, 38 were NHL and 4 HD Most of NHL were diffuse type in which DPDL was the commonest subtype. Retrospective staging according to Ann Arbor staging classification showed 8 to have presented as Stage II, 4 as Stage III and 10 as IV, Clinical follow-up was available in 31 cases in which 5 year survival rate of them was 83.3% in Stage I, 46.2% in Stage I and II, and no case in Stage III and IV. The results of this study would indicate that the prognostically important factor seems to be the stage of disease at the time of diagnosis, but not to be histological subtype.