거대 위궤양에서 발견된 집락형성형 모균증(Mucormycosis) 1예

Mucormycosis is an uncommon, frequently fatal opportunistic infection. Mucormycosis of the gastrointestinal tract is usually found in patients suffering from chronic illness and is thought to arise from fungi entering the body through food. When gastric mucormycosis is presented as an invasive fungal infection, the prognosis is extremely poor. But when the fungus colonizes on the gastric mucosa or on necrotic debris without invasion of the blood vessels, the prognosis is good. A case is herein reported of a colonization type of gastric mucormycosis in a 46 year old male alcoholic. On histologic examination, characteristic findings of nonseptate hyphae with right angle branchings were observed in the ulcer debris without tissue or vessel invasion. Also, the broad and ribbon-like aseptate hyphae was noted on the fungus culture. The patient was treated with nystatin syrup and a proton pump inhibitor without systemic antifungal therapy. (Korean J Gastrointest Endosc 2000;20:49~52)