내시경적 역행성 담췌관조영술 시 예방적 항생제 투여의 유용성

Background/Aims: Prophylactic antibiotics are used in an attempt to avoid the septic complications of endoscopic retrograde cholangiopancreatography (ERCP). But, there is individual tendency to choose prophylactic antibiotics due to a lack of definite guidelines for prophylactic antibiotics. Therefo...

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Veröffentlicht in:Taehan Sohwagi Naesigyŏng Hakhoe chi 1999-12, Vol.19 (6), p.925
Hauptverfasser: 김창섭, Chang Seop Kim, 이규택, Kyu Taek Lee, 이종균, Jong Kyun Lee, 심상군, Sang Goon Shim, 최문석, Mun Suk Choi, 성인경, In Kyung Sung, 이풍렬, Poong Lyul Rhee, 김재준, Jae Jun Kim, 고광철, Kwang Cheol Koh, 백승운, Seung Woon Paik, 이종철, Jong Chul Rhee, 최규완, Kyoo Wan Choi
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container_issue 6
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container_title Taehan Sohwagi Naesigyŏng Hakhoe chi
container_volume 19
creator 김창섭
Chang Seop Kim
이규택
Kyu Taek Lee
이종균
Jong Kyun Lee
심상군
Sang Goon Shim
최문석
Mun Suk Choi
성인경
In Kyung Sung
이풍렬
Poong Lyul Rhee
김재준
Jae Jun Kim
고광철
Kwang Cheol Koh
백승운
Seung Woon Paik
이종철
Jong Chul Rhee
최규완
Kyoo Wan Choi
description Background/Aims: Prophylactic antibiotics are used in an attempt to avoid the septic complications of endoscopic retrograde cholangiopancreatography (ERCP). But, there is individual tendency to choose prophylactic antibiotics due to a lack of definite guidelines for prophylactic antibiotics. Therefore, the effectiveness of ciprofloxacin to prevent post ERCP infectious complications was evaluated. Methods: One hundred patients underwent 75 diagnostic ERCPs and 25, therapeutic ERCPs. They were classified randomly into a group of 51 prophylaxis (ciprofloxacin 200 mg i.v. 30 min before the procedure) and 49 controls. Pre- and post-ERCP blood cultures were prospectively performed and surveyed for infectious complications. Results: Sepsis was detected in 4 patients in each group (p>0.05). Two cases were related to diagnostic ERCP and the remaining six cases, therapeutic ERCP (p<0.01). Bacteremia was found in 6 cases, but only two cases (Escherichia coli, Citrobacter freundii) were clinically significant. Conclusions: The frequency of sepsis following ERCP was not significantly reduced by antibiotic prophylaxis (7.8% vs. 8.2%). (Korean J Gastrointest Endosc 19: 925∼929, 1999)
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But, there is individual tendency to choose prophylactic antibiotics due to a lack of definite guidelines for prophylactic antibiotics. Therefore, the effectiveness of ciprofloxacin to prevent post ERCP infectious complications was evaluated. Methods: One hundred patients underwent 75 diagnostic ERCPs and 25, therapeutic ERCPs. They were classified randomly into a group of 51 prophylaxis (ciprofloxacin 200 mg i.v. 30 min before the procedure) and 49 controls. Pre- and post-ERCP blood cultures were prospectively performed and surveyed for infectious complications. Results: Sepsis was detected in 4 patients in each group (p>0.05). Two cases were related to diagnostic ERCP and the remaining six cases, therapeutic ERCP (p<0.01). Bacteremia was found in 6 cases, but only two cases (Escherichia coli, Citrobacter freundii) were clinically significant. Conclusions: The frequency of sepsis following ERCP was not significantly reduced by antibiotic prophylaxis (7.8% vs. 8.2%). 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(Korean J Gastrointest Endosc 19: 925∼929, 1999)</abstract><pub>대한소화기내시경학회</pub><tpages>5</tpages></addata></record>
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source KoreaMed Open Access; EZB-FREE-00999 freely available EZB journals
subjects Antibiotic prophylaxis
Endoscopic retrograde cholangiopancreatography
title 내시경적 역행성 담췌관조영술 시 예방적 항생제 투여의 유용성
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