조직아교를 이용하여 Hydroxyapatite 에 부착된 연골세포의 배양
Chondrocytes were obtained from femoral condyle of the rabbits and were cultured in the hydroxyapatite (HA) block with tissue glue. Scanning electron micrographs showed that outer surface and the inside of pores of HA were fiUed with cultured cells, and specific morphologic characteristic of chondro...
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| Veröffentlicht in: | Knee surgery & related research 1995-12, Vol.7 (2), p.91 |
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| container_title | Knee surgery & related research |
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| creator | 이은우 강수용 장의찬 정상인 이상엽 Eun Woo Lee Soo Yong Kang Eui Chan Jang Sang In Chung Sang Yup Lee |
| description | Chondrocytes were obtained from femoral condyle of the rabbits and were cultured in the hydroxyapatite (HA) block with tissue glue. Scanning electron micrographs showed that outer surface and the inside of pores of HA were fiUed with cultured cells, and specific morphologic characteristic of chondrocyte was maintained after cultivation for 2 weeks. This composite grdt was implanted into osteachondral defect in the patellar groove of the rabbit femur to examiae the biologic effect of HA to the cultured chondrocyte. Hyaline-like cartilage matrix surmundirig the cells was present as early as 2 weeks implantation. The defect was filled with hyaline-like cartilage, HA was partiaIly resorbed in which the chondrocyte underwent hypertrophic degeneration toward bone formation. This results suggest that HA has a role of biocompatible carrier to transport the chondrocytes and this composite graft may be useful for the treatment of osteochondral defect. |
| format | Article |
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Scanning electron micrographs showed that outer surface and the inside of pores of HA were fiUed with cultured cells, and specific morphologic characteristic of chondrocyte was maintained after cultivation for 2 weeks. This composite grdt was implanted into osteachondral defect in the patellar groove of the rabbit femur to examiae the biologic effect of HA to the cultured chondrocyte. Hyaline-like cartilage matrix surmundirig the cells was present as early as 2 weeks implantation. The defect was filled with hyaline-like cartilage, HA was partiaIly resorbed in which the chondrocyte underwent hypertrophic degeneration toward bone formation. 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Scanning electron micrographs showed that outer surface and the inside of pores of HA were fiUed with cultured cells, and specific morphologic characteristic of chondrocyte was maintained after cultivation for 2 weeks. This composite grdt was implanted into osteachondral defect in the patellar groove of the rabbit femur to examiae the biologic effect of HA to the cultured chondrocyte. Hyaline-like cartilage matrix surmundirig the cells was present as early as 2 weeks implantation. The defect was filled with hyaline-like cartilage, HA was partiaIly resorbed in which the chondrocyte underwent hypertrophic degeneration toward bone formation. 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Scanning electron micrographs showed that outer surface and the inside of pores of HA were fiUed with cultured cells, and specific morphologic characteristic of chondrocyte was maintained after cultivation for 2 weeks. This composite grdt was implanted into osteachondral defect in the patellar groove of the rabbit femur to examiae the biologic effect of HA to the cultured chondrocyte. Hyaline-like cartilage matrix surmundirig the cells was present as early as 2 weeks implantation. The defect was filled with hyaline-like cartilage, HA was partiaIly resorbed in which the chondrocyte underwent hypertrophic degeneration toward bone formation. This results suggest that HA has a role of biocompatible carrier to transport the chondrocytes and this composite graft may be useful for the treatment of osteochondral defect.</abstract><pub>대한슬관절학회</pub><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2234-0726 |
| ispartof | Knee surgery & related research, 1995-12, Vol.7 (2), p.91 |
| issn | 2234-0726 |
| language | kor |
| recordid | cdi_kiss_primary_1838928 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Chondrocytes Hydroxyapatite Osteochondral defects |
| title | 조직아교를 이용하여 Hydroxyapatite 에 부착된 연골세포의 배양 |
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