Multicentric Castleman Disease with Cutaneous Manifestations: Report of 2 Cases and Comparison with Systemic Plasmacytosis

We report 2 patients with multicentric Castleman disease. Both presented with multiple, indurated, hyperpigmented plaques, generalized lymphadenopathy and polyclonal hypergammaglobulinemia. Biopsy specimens showed infiltration of mature plasma cells and lymphocytes in the dermis and lymph nodes. Ski...

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Veröffentlicht in:	Dermatology (Basel) 2007-01, Vol.214 (2), p.170-173
Hauptverfasser:	Higashi, Yuko, Kanekura, Takuro, Sakamoto, Ryoko, Mochitomi, Yuji, Kanzaki, Tamotsu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Biopsy Case Report Case studies Castleman Disease - diagnosis Castleman Disease - pathology Cell Proliferation Dermatology Epstein-Barr virus Female Hematologic and hematopoietic diseases Human herpesvirus 8 Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphatic Diseases - diagnosis Lymphatic Diseases - pathology Lymphocytes - pathology Male Medical sciences Middle Aged Plasma Cells - pathology Skin - pathology Skin Diseases - diagnosis Skin Diseases - pathology T cell receptors Tumors
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