Sympathectomy Causes Aggravated Lesions and Dedifferentiation in Large Rabbit Atherosclerotic Arteries without Involving Nitric Oxide

Previously [Histochem J 1997;29:279–286], we found that sympathectomy induced neointima formation in ear but not cerebral arteries of genetically hyperlipidemic rabbits. To clarify the influence of sympathetic nerves in atherosclerosis, and whether their influence involves vascular NO activity, we s...

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Veröffentlicht in:	Journal of vascular research 2006-01, Vol.43 (3), p.289-305
Hauptverfasser:	Kacem, Kamel, Sercombe, Christine, Hammami, Mohamed, Vicaut, Eric, Sercombe, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Animals Atherosclerosis (general aspects, experimental research) Atherosclerosis - etiology Atherosclerosis - metabolism Atherosclerosis - pathology Basilar Artery - drug effects Basilar Artery - innervation Basilar Artery - metabolism Basilar Artery - pathology Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cell Differentiation Cell Movement Cell Proliferation Disease Models, Animal Disorders of blood lipids. Hyperlipoproteinemia Dose-Response Relationship, Drug Enzyme Inhibitors - pharmacology Femoral Artery - drug effects Femoral Artery - innervation Femoral Artery - metabolism Femoral Artery - pathology Fundamental and applied biological sciences. Psychology Hypercholesterolemia - pathology Male Medical sciences Metabolic diseases Nitric Oxide - metabolism Nitric Oxide Synthase - antagonists & inhibitors Nitric Oxide Synthase - metabolism Nitroarginine - pharmacology Oxidopamine Rabbits Research Paper Sympathectomy, Chemical Tunica Intima - pathology Tunica Media - pathology Vasodilator Agents - pharmacology Vertebrates: cardiovascular system
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