Stereological Evaluation of the Seminiferous Tubules of Rats after Maternal Undernutrition during the Lactation Period

The goal of this study is to evaluate, through stereological methods, some structural aspects of offspring testes whose dams were submitted to protein and energy-restricted diets during the lactation period. At birth, dams were separated into 3 groups: control group (C), receiving a diet with 23% pr...

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Veröffentlicht in:Urologia internationalis 2006-01, Vol.76 (1), p.63-66
Hauptverfasser: Ramos, Cristiane da Fonte, da Silva, Alexandra Moreira, Costa, Waldemar Silva, Sampaio, Francisco J.B.
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container_end_page 66
container_issue 1
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container_title Urologia internationalis
container_volume 76
creator Ramos, Cristiane da Fonte
da Silva, Alexandra Moreira
Costa, Waldemar Silva
Sampaio, Francisco J.B.
description The goal of this study is to evaluate, through stereological methods, some structural aspects of offspring testes whose dams were submitted to protein and energy-restricted diets during the lactation period. At birth, dams were separated into 3 groups: control group (C), receiving a diet with 23% protein; protein-restricted group (PR), receiving a diet with 8% protein; energy-restricted group (ER), receiving a diet with 23% protein in restricted quantities. At weaning, the offspring was anesthetized and perfused with formalin solution. Then, the testes were excised and processed using routine histological methods. Compared to the C group, both PR and ER groups had a significant reduction in the testis weight (PR = 65%, ER = 60%, p < 0.01), in the total area (PR = 23%, ER = 32%, p < 0.01), in the luminal area (PR = 30%, ER = 36%, p < 0.01), in the epithelial area (PR = 21%, ER = 27%, p < 0.01), and in the epithelial height (PR = 17%, ER = 23%, p < 0.01) of the seminiferous tubule. We conclude that maternal malnutrition during lactation leads to structural changes in the testis that could be responsible for future alterations in this organ physiology.
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We conclude that maternal malnutrition during lactation leads to structural changes in the testis that could be responsible for future alterations in this organ physiology.</abstract><cop>Basel, Switzerland</cop><pmid>16401923</pmid><doi>10.1159/000089737</doi><tpages>4</tpages></addata></record>
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source MEDLINE; Karger Journals
subjects Animal Nutritional Physiological Phenomena
Animals
Animals, Newborn
Lactation
Male
Maternal Nutritional Physiological Phenomena
Organ Size
Original Paper
Protein-Energy Malnutrition
Rats
Rats, Wistar
Seminiferous Tubules - pathology
Testis - pathology
title Stereological Evaluation of the Seminiferous Tubules of Rats after Maternal Undernutrition during the Lactation Period
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