Peroxynitrite Modulates Release of Inflammatory Mediators from Guinea Pig Lung Mast Cells Activated by Antigen-Antibody Reaction

Background: Peroxynitrite (ONOO – ), the product of the reaction between the superoxide anion (·O 2 – ) and nitric oxide (NO), is produced during inflammatory disease and may be a major cytotoxic agent. No reports are available as to whether ONOO – generates or modulates inflammatory mediator releas...

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