Cytochrome P450-2C11 mRNA Is Not Expressed in Endothelial Cells Dissected from Rat Renal Arterioles

Background: Cytochrome P450 (CYP) isoenzymes (CYP2C and CYP2J) are involved in the production of epoxyeicosatrienoic acids, which are postulated as endothelium-derived hyperpolarizing factors (EDHFs). We hypothesized that if CYP2C11 is involved in the EDHF-mediated responses, its mRNA should be expr...

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Veröffentlicht in:	Nephron 2005-02, Vol.99 (2), p.p43-p49
Hauptverfasser:	Heil, Sandra G., De Vriese, An S., Kluijtmans, Leo A.J., Dijkman, Henry, van Strien, Denise, Akkers, Robert, Blom, Henk J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arterioles - enzymology Aryl Hydrocarbon Hydroxylases - genetics Aryl Hydrocarbon Hydroxylases - metabolism Cells, Cultured Cytochrome P450 Family 2 Endothelial Cells - enzymology Female In Vitro Techniques Kidney - blood supply Kidney - enzymology Male Original Paper Rats Rats, Wistar RNA, Messenger - metabolism Steroid 16-alpha-Hydroxylase - genetics Steroid 16-alpha-Hydroxylase - metabolism
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