The Potential Use of Stem Cells for Cochlear Repair
In light of the currently defined characteristics of stem cells, a re-evaluation of hair cell regeneration in birds suggests that there may be a stem cell population located in the inner ear. It is yet to be determined if the mammalian cochlea contains stem cells, but the presence of a mammalian ves...
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| Veröffentlicht in: | Audiology & neurotology 2004-03, Vol.9 (2), p.72-80 |
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| container_title | Audiology & neurotology |
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| creator | Parker, Mark A. Cotanche, Douglas A. |
| description | In light of the currently defined characteristics of stem cells, a re-evaluation of hair cell regeneration in birds suggests that there may be a stem cell population located in the inner ear. It is yet to be determined if the mammalian cochlea contains stem cells, but the presence of a mammalian vestibular stem cell population would not appear to be out of the realm of possibility. This paper reviews the latest advances in stem cell biology and suggests that stem cells may be an appropriate biological tool to be used for cochlear repair. The potential use of several types of stem cells, including embryonic, neural and hematopoietic stem cells, as agents for cochlear repair is examined. |
| doi_str_mv | 10.1159/000075998 |
| format | Article |
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It is yet to be determined if the mammalian cochlea contains stem cells, but the presence of a mammalian vestibular stem cell population would not appear to be out of the realm of possibility. This paper reviews the latest advances in stem cell biology and suggests that stem cells may be an appropriate biological tool to be used for cochlear repair. The potential use of several types of stem cells, including embryonic, neural and hematopoietic stem cells, as agents for cochlear repair is examined.</description><identifier>ISSN: 1420-3030</identifier><identifier>EISSN: 1421-9700</identifier><identifier>DOI: 10.1159/000075998</identifier><identifier>PMID: 14981355</identifier><language>eng</language><publisher>Basel, Switzerland: Karger</publisher><subject>Animals ; Biological and medical sciences ; Blastocyst - cytology ; Cell Differentiation ; Cochlea - cytology ; Cochlea - physiology ; Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology ; Hair Cells, Auditory - physiology ; Hearing Loss - therapy ; Hematopoietic Stem Cells - physiology ; Humans ; Medical sciences ; Non tumoral diseases ; Otorhinolaryngology. 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The potential use of several types of stem cells, including embryonic, neural and hematopoietic stem cells, as agents for cochlear repair is examined.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Blastocyst - cytology</subject><subject>Cell Differentiation</subject><subject>Cochlea - cytology</subject><subject>Cochlea - physiology</subject><subject>Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology</subject><subject>Hair Cells, Auditory - physiology</subject><subject>Hearing Loss - therapy</subject><subject>Hematopoietic Stem Cells - physiology</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Non tumoral diseases</subject><subject>Otorhinolaryngology. 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| source | Karger Journals; MEDLINE |
| subjects | Animals Biological and medical sciences Blastocyst - cytology Cell Differentiation Cochlea - cytology Cochlea - physiology Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology Hair Cells, Auditory - physiology Hearing Loss - therapy Hematopoietic Stem Cells - physiology Humans Medical sciences Non tumoral diseases Otorhinolaryngology. Stomatology Regeneration - physiology Review Stem Cell Transplantation - methods Stem Cells - cytology Stem Cells - physiology |
| title | The Potential Use of Stem Cells for Cochlear Repair |
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