IGF-I Transcript Levels in Whole-Liver Tissue, in Freshly Isolated Hepatocytes, and in Cultured Hepatocytes from Lean and Obese Zucker Rats

Background: The mechanisms underlying the maintenance of normal to high rates of linear growth and plasma insulin-like growth factor I (IGF-I) levels in spite of a low growth hormone secretion in obese children remain unknown. Among the animal models of early-onset obesity, obese Zucker (fa/fa) rats...

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Veröffentlicht in:	Hormone research 2003-01, Vol.59 (3), p.135-141, Article 135
Hauptverfasser:	Tenoutasse, S., van Vliet, G., Ledru, E., Deal, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Weight - physiology Cell Separation Cells, Cultured DNA, Complementary - biosynthesis DNA, Complementary - genetics Hepatocytes - immunology Hepatocytes - metabolism In Vitro Techniques Insulin-Like Growth Factor I - biosynthesis Liver - immunology Liver - metabolism Male Obesity - immunology Obesity - metabolism Original Paper Rats Rats, Zucker Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis Transcription, Genetic
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