Case Report of a Benign Granular Cell Tumor Resembling Breast Carcinoma in a Young Woman: A Diagnostic Challenge
Abstract Introduction: Granular cell tumors (GCTs) are uncommon, low-grade Schwann cell tumors found in the skin, soft tissue, and mucosal surfaces of the oral, gastrointestinal, and respiratory tracts. One in 1,000 breast cancer cases is GCT. Just 1–2% of GCTs are malignant GCTs. Case Presentation:...
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| Veröffentlicht in: | Case reports in oncology 2024-01, Vol.17 (1), p.608-613 |
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| creator | Akbari, Atieh Behravan, Parisa Moradi, Afshin Akbari, Mohammad Esmaeil |
| description | Abstract
Introduction: Granular cell tumors (GCTs) are uncommon, low-grade Schwann cell tumors found in the skin, soft tissue, and mucosal surfaces of the oral, gastrointestinal, and respiratory tracts. One in 1,000 breast cancer cases is GCT. Just 1–2% of GCTs are malignant GCTs. Case Presentation: This case report presents the clinical details and outcomes of a 34-year-old woman with a main concern of a palpable mass and pain in her right breast. In the clinical examination, we found a 1.5 × 2-cm palpable mass in her right breast with no axillary lymph node detection. The primary diagnosis was a benign GCT mimicking carcinoma of the breast. Upon evaluation, the mass was confirmed to be a benign GCT through pathology. The patient underwent breast-conserving surgery and sentinel lymph node dissection at the Cancer Research Center of Shahid Beheshti University of Medical Sciences on November 30, 2022. The surgical margins were found to be free of tumors, and there was no involvement of skin or axillary lymph nodes. The patient had a positive postoperative outcome, with no complications observed. Conclusion: The case highlights the importance of accurate diagnosis and appropriate surgical planning to avoid invasive procedures and unnecessary radical surgeries in cases of benign GCT mimicking carcinoma of the breast. |
| doi_str_mv | 10.1159/000538771 |
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Introduction: Granular cell tumors (GCTs) are uncommon, low-grade Schwann cell tumors found in the skin, soft tissue, and mucosal surfaces of the oral, gastrointestinal, and respiratory tracts. One in 1,000 breast cancer cases is GCT. Just 1–2% of GCTs are malignant GCTs. Case Presentation: This case report presents the clinical details and outcomes of a 34-year-old woman with a main concern of a palpable mass and pain in her right breast. In the clinical examination, we found a 1.5 × 2-cm palpable mass in her right breast with no axillary lymph node detection. The primary diagnosis was a benign GCT mimicking carcinoma of the breast. Upon evaluation, the mass was confirmed to be a benign GCT through pathology. The patient underwent breast-conserving surgery and sentinel lymph node dissection at the Cancer Research Center of Shahid Beheshti University of Medical Sciences on November 30, 2022. The surgical margins were found to be free of tumors, and there was no involvement of skin or axillary lymph nodes. The patient had a positive postoperative outcome, with no complications observed. Conclusion: The case highlights the importance of accurate diagnosis and appropriate surgical planning to avoid invasive procedures and unnecessary radical surgeries in cases of benign GCT mimicking carcinoma of the breast.</description><identifier>ISSN: 1662-6575</identifier><identifier>EISSN: 1662-6575</identifier><identifier>DOI: 10.1159/000538771</identifier><identifier>PMID: 39015632</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>breast ; Breast cancer ; Cancer research ; Cancer therapies ; Case Report ; Case reports ; Cytoplasm ; Estrogens ; granular cell tumor ; Informed consent ; Lymphatic system ; Mammography ; Medical diagnosis ; Medical prognosis ; Medical research ; Pathology ; Personal information ; schwann cells ; Surveillance ; Tumors ; Ultrasonic imaging ; uncommon tumors</subject><ispartof>Case reports in oncology, 2024-01, Vol.17 (1), p.608-613</ispartof><rights>2024 The Author(s). Published by S. Karger AG, Basel</rights><rights>2024 The Author(s). Published by S. Karger AG, Basel.</rights><rights>2024 The Author(s). Published by S. Karger AG, Basel. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the associated terms available at: https://uk.sagepub.com/en-gb/eur/reusing-open-access-and-sage-choice-content</rights><rights>2024 The Author(s). Published by S. Karger AG, Basel 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11250677/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11250677/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,2103,27640,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39015632$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Akbari, Atieh</creatorcontrib><creatorcontrib>Behravan, Parisa</creatorcontrib><creatorcontrib>Moradi, Afshin</creatorcontrib><creatorcontrib>Akbari, Mohammad Esmaeil</creatorcontrib><title>Case Report of a Benign Granular Cell Tumor Resembling Breast Carcinoma in a Young Woman: A Diagnostic Challenge</title><title>Case reports in oncology</title><addtitle>Case Rep Oncol</addtitle><description>Abstract
Introduction: Granular cell tumors (GCTs) are uncommon, low-grade Schwann cell tumors found in the skin, soft tissue, and mucosal surfaces of the oral, gastrointestinal, and respiratory tracts. One in 1,000 breast cancer cases is GCT. Just 1–2% of GCTs are malignant GCTs. Case Presentation: This case report presents the clinical details and outcomes of a 34-year-old woman with a main concern of a palpable mass and pain in her right breast. In the clinical examination, we found a 1.5 × 2-cm palpable mass in her right breast with no axillary lymph node detection. The primary diagnosis was a benign GCT mimicking carcinoma of the breast. Upon evaluation, the mass was confirmed to be a benign GCT through pathology. The patient underwent breast-conserving surgery and sentinel lymph node dissection at the Cancer Research Center of Shahid Beheshti University of Medical Sciences on November 30, 2022. The surgical margins were found to be free of tumors, and there was no involvement of skin or axillary lymph nodes. The patient had a positive postoperative outcome, with no complications observed. Conclusion: The case highlights the importance of accurate diagnosis and appropriate surgical planning to avoid invasive procedures and unnecessary radical surgeries in cases of benign GCT mimicking carcinoma of the breast.</description><subject>breast</subject><subject>Breast cancer</subject><subject>Cancer research</subject><subject>Cancer therapies</subject><subject>Case Report</subject><subject>Case reports</subject><subject>Cytoplasm</subject><subject>Estrogens</subject><subject>granular cell tumor</subject><subject>Informed consent</subject><subject>Lymphatic system</subject><subject>Mammography</subject><subject>Medical diagnosis</subject><subject>Medical prognosis</subject><subject>Medical research</subject><subject>Pathology</subject><subject>Personal information</subject><subject>schwann cells</subject><subject>Surveillance</subject><subject>Tumors</subject><subject>Ultrasonic imaging</subject><subject>uncommon tumors</subject><issn>1662-6575</issn><issn>1662-6575</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>M--</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DOA</sourceid><recordid>eNpdkktv1TAQhSMEog9YsEfIEhs2F_yI7YRN1QYolSpVqooQK2sST1JfEvtiJ0j991iklLYr23M-nzkauyheMfqeMVl_oJRKUWnNnhT7TCm-UVLLp_f2e8VBSltKVS2VfF7siZoyqQTfL3YNJCSXuAtxJqEnQE7Qu8GT0wh-GSGSBseRXC1TiBlLOLWj8wM5iQhpJg3EzvkwAXE-3_0Rlqx9z2f_kRyTTw4GH9LsOtJcwziiH_BF8ayHMeHL2_Ww-Pbl81XzdXN-cXrWHJ9vrNBy3si-xL4tRQ29xl6BsBVnaCu0DBnWTEqsBbcdb0FLVupOcezaurJlXbWagzgszlZfG2BrdtFNEG9MAGf-FkIcDMScbERTlhXnutdd22JpNYAAXVEh80QrZvsyex2tXrulndB26OcI4wPTh4p312YIvw1jXFKldXZ4d-sQw68F02wml7o8WfAYlmQErVjuxpXM6NtH6DYs0edZZUpTSWsuRabe3I90l-Xfy2bg9Qr8hDhgvAPWj_K_yyO5ubxYCbOzvfgDo-S5Fw</recordid><startdate>20240101</startdate><enddate>20240101</enddate><creator>Akbari, Atieh</creator><creator>Behravan, Parisa</creator><creator>Moradi, Afshin</creator><creator>Akbari, Mohammad Esmaeil</creator><general>S. 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Introduction: Granular cell tumors (GCTs) are uncommon, low-grade Schwann cell tumors found in the skin, soft tissue, and mucosal surfaces of the oral, gastrointestinal, and respiratory tracts. One in 1,000 breast cancer cases is GCT. Just 1–2% of GCTs are malignant GCTs. Case Presentation: This case report presents the clinical details and outcomes of a 34-year-old woman with a main concern of a palpable mass and pain in her right breast. In the clinical examination, we found a 1.5 × 2-cm palpable mass in her right breast with no axillary lymph node detection. The primary diagnosis was a benign GCT mimicking carcinoma of the breast. Upon evaluation, the mass was confirmed to be a benign GCT through pathology. The patient underwent breast-conserving surgery and sentinel lymph node dissection at the Cancer Research Center of Shahid Beheshti University of Medical Sciences on November 30, 2022. The surgical margins were found to be free of tumors, and there was no involvement of skin or axillary lymph nodes. The patient had a positive postoperative outcome, with no complications observed. Conclusion: The case highlights the importance of accurate diagnosis and appropriate surgical planning to avoid invasive procedures and unnecessary radical surgeries in cases of benign GCT mimicking carcinoma of the breast.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>39015632</pmid><doi>10.1159/000538771</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | breast Breast cancer Cancer research Cancer therapies Case Report Case reports Cytoplasm Estrogens granular cell tumor Informed consent Lymphatic system Mammography Medical diagnosis Medical prognosis Medical research Pathology Personal information schwann cells Surveillance Tumors Ultrasonic imaging uncommon tumors |
| title | Case Report of a Benign Granular Cell Tumor Resembling Breast Carcinoma in a Young Woman: A Diagnostic Challenge |
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