Emergence of Spatial Scales and Macroscopic Tissue Dynamics in Active Epithelial Monolayers

Abstract Migrating cells in tissues are often known to exhibit collective swirling movements. In this paper, we develop an active vertex model with polarity dynamics based on contact inhibition of locomotion (CIL). We show that under this dynamics, the cells form steady-state vortices in velocity, p...

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Veröffentlicht in:	Cells, tissues, organs tissues, organs, 2024, Vol.213 (4), p.269-282
Hauptverfasser:	Selvamani, Padmalochini, Chelakkot, Raghunath, Nandi, Amitabha, Inamdar, Mandar M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomechanical Phenomena Cell Movement - physiology Cell Polarity - physiology Epithelial Cells - cytology Humans Models, Biological Research Article
Online-Zugang:	Volltext
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