Structure-Function Relationships of the α1b-Adrenergic Receptor

The α 1b -adrenergic receptor (AR) is a member of the large superfamily of seven transmembrane domain (TMD) G protein-coupled receptors (GPCR). Combining site-directed mutagenesis of the α 1b -AR with computational simulations of receptor dynamics, we have explored the conformational changes underly...

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Veröffentlicht in:	European urology 1999-01, Vol.36 (Suppl 1), p.11-16
Hauptverfasser:	Scheer, A., Fanelli, F., Diviani, D., de Benedetti, P.G., Cotecchia, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Molecular Biology and Pharmacology of α1-Adrenoceptors
Online-Zugang:	Volltext
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