Low Geriatric Nutritional Risk Index as a Poor Prognostic Marker for Second-Line Pembrolizumab Treatment in Patients with Metastatic Urothelial Carcinoma: A Retrospective Multicenter Analysis

Background: We evaluated the prognostic efficacy of the Geriatric Nutritional Risk Index (GNRI) in second-line pembrolizumab (PEM) therapy for patients with metastatic urothelial carcinoma (mUC). Patients and Methods: From January 2018 to October 2019, 52 mUC patients, treated previously with platin...

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Veröffentlicht in:	Oncology 2020-11, Vol.98 (12), p.876-883
Hauptverfasser:	Etani, Toshiki, Naiki, Taku, Sugiyama, Yosuke, Nagai, Takashi, Iida, Keitaro, Noda, Yusuke, Shimizu, Nobuhiko, Tasaki, Yoshihiko, Mimura, Yoshihisa, Okada, Tomoki, Banno, Rika, Kubota, Hiroki, Hamamoto, Shuzo, Ando, Ryosuke, Kawai, Noriyasu, Yasui, Takahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antibodies, Monoclonal, Humanized - administration & dosage Antibodies, Monoclonal, Humanized - adverse effects Biomarkers, Tumor - blood Biomarkers, Tumor - genetics Bladder cancer Body Weight C-Reactive Protein - metabolism Carcinoma - blood Carcinoma - drug therapy Carcinoma - pathology Care and treatment Clinical Study Diagnosis Female Geriatric Assessment Humans Lymphocytes - pathology Male Metastasis Middle Aged Neoplasm Metastasis Neoplasm Recurrence, Local Neutrophils - pathology Nutrition Assessment Prognosis Progression-Free Survival Retrospective Studies Risk Factors Urothelium - drug effects Urothelium - pathology
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