Post-Transplant Cyclophosphamide Combined with Anti-Thymocyte Globulin as Graft-versus-Host Disease Prophylaxis for Allogeneic Hematopoietic Cell Transplantation in High-Risk Acute Myeloid Leukemia and Myelodysplastic Syndrome

Background: Allogeneic hematopoietic cell transplantation (HCT) is curative for high-risk acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but with significant non-relapse mortality (NRM) and relapse. We compared the combination of anti-thymocyte globulin (ATG; 4.5 mg/kg) and post-tra...

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Veröffentlicht in:	ACTA HAEMATOLOGICA 2021-01, Vol.144 (1), p.66-73
Hauptverfasser:	Alanazi, Wael, Chen, Shiyi, Lipton, Jeffrey H., Kim, Dennis D., Viswabandya, Auro, Kumar, Rajat, Lam, Wilson, Law, Arjun D., Al-Shaibani, Zeyad, Mattsson, Jonas, Michelis, Fotios V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antilymphocyte Serum - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Cause of Death Cyclophosphamide - administration & dosage Female Graft vs Host Disease - etiology Graft vs Host Disease - prevention & control Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - methods Humans Leukemia, Myeloid, Acute - complications Leukemia, Myeloid, Acute - diagnosis Leukemia, Myeloid, Acute - etiology Leukemia, Myeloid, Acute - therapy Male Middle Aged Myelodysplastic Syndromes - complications Myelodysplastic Syndromes - diagnosis Myelodysplastic Syndromes - etiology Myelodysplastic Syndromes - therapy Neoplasm Staging Original Paper Postoperative Care Prognosis Recurrence Retrospective Studies Tissue Donors Transplantation Conditioning Transplantation, Homologous Treatment Outcome Young Adult
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