Pharmacokinetics of Total and Unbound Cefazolin during Veno-Arterial Extracorporeal Membrane Oxygenation: A Case Report

Extra-corporeal membrane oxygenation (ECMO) therapy could affect effective drug concentrations via adsorption onto the oxygenator or associated circuit. We describe a case of a 25-year-old female who required a veno-arterial ECMO therapy for refractory cardiac arrest due to massive pulmonary embolis...

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Veröffentlicht in:	Chemotherapy (Basel) 2019-11, Vol.64 (3), p.115-118
Hauptverfasser:	Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H., Roberts, Jason A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antimicrobial Section / Case Report Area Under Curve Cefazolin - administration & dosage Cefazolin - blood Cefazolin - metabolism Extracorporeal Membrane Oxygenation Female Half-Life Heart Arrest - complications Heart Arrest - diagnosis Humans Protein Binding Pulmonary Embolism - complications Pulmonary Embolism - pathology ROC Curve
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