Prognostic Implication of Urothelial Stem Cell Markers Differs According to Primary Tumour Location in Non-Muscle-Invasive Bladder Cancer

Background/Aims: This study aimed to validate the value of urothelial stem cell (USC) markers ΔNp63, integrin β4, CD47, and CD44v6 in predicting the prognosis of non-muscle invasive bladder cancer (NMIBC) located in different anatomic regions of bladder. Methods: The study reviewed the clinicopathol...

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Veröffentlicht in:	Cellular Physiology and Biochemistry 2018-08, Vol.48 (6), p.2364-2373
Hauptverfasser:	Wang, Longwang, Zhao, Jun, Yang, Chenlu, Kuang, Renrui, Kazobinka, Gallina, Pang, Zili, Hou, Teng
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Bladder cancer Breast cancer Cancer therapies CD47 Antigen - genetics CD47 Antigen - metabolism Chemotherapy Disease-Free Survival Female Health aspects Humans Hyaluronan Receptors - genetics Hyaluronan Receptors - metabolism Immunohistochemistry Integrin beta4 - genetics Integrin beta4 - metabolism Kaplan-Meier Estimate Male Medical prognosis Middle Aged Morphology Neoplasm Staging NMIBC Original Paper Physiological aspects Posterior wall Prognosis Proportional Hazards Models RFS Stem cell marker Stem cells Transcription Factors - genetics Transcription Factors - metabolism Trigone Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism Tumorigenesis Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - mortality Urinary Bladder Neoplasms - pathology
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